Age-related pharmacokinetic and pharmacodynamic changes and related risk of adverse drug reactions

A Corsonello, C Pedone… - Current medicinal …, 2010 - ingentaconnect.com
Aging is known to be associated with an increased prevalence of multiple chronic diseases,
which frequently causes the use of complex therapeutic regimens. The aging process is …

[HTML][HTML] Prevalence of chronic renal disease in Spain: results of the EPIRCE study

A Otero González, A de Francisco… - Nefrología (English …, 2010 - revistanefrologia.com
Introduction: Chronic kidney disease (CKD) is an independent cardiovascular risk factor.
The knowledge of prevalence in general population may help to early detection of CKD and …

Nephrotoxicity—what do we know and what don't we know?

R Skinner - Journal of pediatric hematology/oncology, 2011 - journals.lww.com
Nephrotoxicity is the development of functional or structural kidney damage after exposure
to one or more of a wide variety of drugs, other treatments or exogenous toxins, and may …

Performance of creatinine-based GFR estimating equations in solid-organ transplant recipients

K Shaffi, K Uhlig, RD Perrone, R Ruthazer… - American Journal of …, 2014 - Elsevier
Background Accurate assessment of kidney function is important for the management of
solid-organ transplant recipients. In other clinical populations, glomerular filtration rate …

[HTML][HTML] For estimating creatinine clearance measuring muscle mass gives better results than those based on demographics

AD Rule, KR Bailey, GL Schwartz, S Khosla… - Kidney international, 2009 - Elsevier
Estimation of creatinine clearance requires knowledge of creatinine generation which can
vary in different groups of patients. Since the main source of creatinine is muscle we used …

MDRD or CKD-EPI study equations for estimating prevalence of stage 3 CKD in epidemiological studies: which difference? Is this difference relevant?

P Delanaye, E Cavalier, C Mariat, N Maillard… - BMC nephrology, 2010 - Springer
Background Prevalence of stage 3 chronic kidney disease (CKD) is increasing according to
the NHANES study. Prevalence has been calculated using the MDRD study equation for …

[HTML][HTML] Prevalencia de la insuficiencia renal crónica en España: Resultados del estudio EPIRCE

A Otero González, A Francisco, P Gayoso… - Nefrología …, 2010 - SciELO Espana
Introducción: La insuficiencia renal crónica (IRC) constituye un factor de riesgo
cardiovascular independiente. El conocimiento de su prevalencia en la población general …

Long‐term follow‐up of renal function in dogs after treatment for ACTH‐dependent hyperadrenocorticism

PMY Smets, HP Lefebvre, BP Meij… - Journal of veterinary …, 2012 - Wiley Online Library
Background Systemic hypertension and proteinuria are frequent complications in dogs with
Cushing's syndrome and do not always resolve after treatment of hypercortisolism …

Vanadium exposure and kidney markers in a pediatric population: a cross-sectional study

E Rojas-Lima, M Ortega-Romero… - Pediatric …, 2024 - Springer
Background Anthropogenic vanadium (V) emissions and exposure in the general population
have recently increased. Experimental studies have shown that V is a nephrotoxic agent, but …

Glomerular function time trends in long-term survivors of childhood cancer: a longitudinal study

RL Mulder, SL Knijnenburg, RB Geskus… - … , biomarkers & prevention, 2013 - AACR
Background: Impaired glomerular function is one of the health problems affecting childhood
cancer survivors (CCS). It is unclear whether glomerular function deteriorates or recovers …