Hallmarks of response, resistance, and toxicity to immune checkpoint blockade

G Morad, BA Helmink, P Sharma, JA Wargo - Cell, 2021 - cell.com
Unprecedented advances have been made in cancer treatment with the use of immune
checkpoint blockade (ICB). However, responses are limited to a subset of patients, and …

Gene–environment interactions and their impact on human health

SJ Virolainen, A VonHandorf, KCMF Viel… - Genes & …, 2023 - nature.com
The molecular processes underlying human health and disease are highly complex. Often,
genetic and environmental factors contribute to a given disease or phenotype in a non …

Tracking complex mixtures of chemicals in our changing environment

BI Escher, HM Stapleton, EL Schymanski - Science, 2020 - science.org
Chemicals have improved our quality of life, but the resulting environmental pollution has
the potential to cause detrimental effects on humans and the environment. People and biota …

The exposome and health: Where chemistry meets biology

R Vermeulen, EL Schymanski, AL Barabási, GW Miller - Science, 2020 - science.org
Despite extensive evidence showing that exposure to specific chemicals can lead to
disease, current research approaches and regulatory policies fail to address the chemical …

Micronucleus assay: the state of art, and future directions

S Sommer, I Buraczewska, M Kruszewski - International journal of …, 2020 - mdpi.com
During almost 40 years of use, the micronucleus assay (MN) has become one of the most
popular methods to assess genotoxicity of different chemical and physical factors, including …

Enhanced permeability and antifouling performance of polyether sulfone (PES) membrane via elevating magnetic Ni@ MXene nanoparticles to upper layer in phase …

Z Huang, J Liu, Y Liu, Y Xu, R Li, H Hong… - Journal of Membrane …, 2021 - Elsevier
In this study, magnetic Ni@ MXene nanoparticles were firstly developed and then elevated
to the upper layer of polyether sulfone (PES) membrane by an external magnetic field during …

Persistent SARS-CoV-2 infection, EBV, HHV-6 and other factors may contribute to inflammation and autoimmunity in long COVID

A Vojdani, E Vojdani, E Saidara, M Maes - Viruses, 2023 - mdpi.com
A novel syndrome called long-haul COVID or long COVID is increasingly recognized in a
significant percentage of individuals within a few months after infection with SARS-CoV-2 …

Characterization of weighted quantile sum regression for highly correlated data in a risk analysis setting

C Carrico, C Gennings, DC Wheeler… - Journal of agricultural …, 2015 - Springer
In risk evaluation, the effect of mixtures of environmental chemicals on a common adverse
outcome is of interest. However, due to the high dimensionality and inherent correlations …

[HTML][HTML] What is new in the exposome?

P Vineis, O Robinson, M Chadeau-Hyam… - Environment …, 2020 - Elsevier
The exposome concept refers to the totality of exposures from a variety of external and
internal sources including chemical agents, biological agents, or radiation, from conception …

Metabolic inflammation in heart failure with preserved ejection fraction

GG Schiattarella, D Rodolico, JA Hill - Cardiovascular research, 2021 - academic.oup.com
One in 10 persons in the world aged 40 years and older will develop the syndrome of
HFpEF (heart failure with preserved ejection fraction), the most common form of chronic …