Biological foundations of successful bacteriophage therapy
C Venturini, A Petrovic Fabijan… - EMBO Molecular …, 2022 - embopress.org
Bacteriophages (phages) are selective viral predators of bacteria. Abundant and ubiquitous
in nature, phages can be used to treat bacterial infections (phage therapy), including …
in nature, phages can be used to treat bacterial infections (phage therapy), including …
Lyme borreliosis diagnosis: State of the art of improvements and innovations
M Guérin, M Shawky, A Zedan, S Octave, B Avalle… - BMC microbiology, 2023 - Springer
With almost 700 000 estimated cases each year in the United States and Europe, Lyme
borreliosis (LB), also called Lyme disease, is the most common tick-borne illness in the …
borreliosis (LB), also called Lyme disease, is the most common tick-borne illness in the …
Thousands of previously unknown phages discovered in whole-community human gut metagenomes
Background Double-stranded DNA bacteriophages (dsDNA phages) play pivotal roles in
structuring human gut microbiomes; yet, the gut virome is far from being fully characterized …
structuring human gut microbiomes; yet, the gut virome is far from being fully characterized …
High cell densities favor lysogeny: induction of an H20 prophage is repressed by quorum sensing and enhances biofilm formation in Vibrio anguillarum
Temperate ϕH20-like phages are repeatedly identified at geographically distinct areas as
free phage particles or as prophages of the fish pathogen Vibrio anguillarum. We studied …
free phage particles or as prophages of the fish pathogen Vibrio anguillarum. We studied …
Induction mechanisms and strategies underlying interprophage competition during polylysogeny
JE Silpe, OP Duddy, BL Bassler - PLoS pathogens, 2023 - journals.plos.org
Phages play central roles in shaping bacterial community biology. For example, lytic
phages, by eliminating particular subpopulations of bacteria, control the composition of …
phages, by eliminating particular subpopulations of bacteria, control the composition of …
[HTML][HTML] Microbiome dynamics and genomic determinants of bovine mastitis
A bstract The milk of lactating cows presents a complex ecosystem of interconnected
microbial communities which can influence the pathophysiology of mastitis. We …
microbial communities which can influence the pathophysiology of mastitis. We …
The enemy of my enemy: new insights regarding bacteriophage–mammalian cell interactions
Bacteriophages (phages) are the most abundant biological entity in the human body, but
until recently the role that phages play in human health was not well characterized. Although …
until recently the role that phages play in human health was not well characterized. Although …
Induction of mastitis by cow-to-mouse fecal and milk microbiota transplantation causes microbiome dysbiosis and genomic functional perturbation in mice
Background Mastitis pathogenesis involves a wide range of opportunistic and apparently
resident microorganims including bacteria, viruses and archaea. In dairy animals, microbes …
resident microorganims including bacteria, viruses and archaea. In dairy animals, microbes …
Aquatic environment drives the emergence of cell wall-deficient dormant forms in Listeria
F Carvalho, A Carreaux, A Sartori-Rupp… - Nature …, 2024 - nature.com
Stressed bacteria can enter a dormant viable but non-culturable (VBNC) state. VBNC
pathogens pose an increased health risk as they are undetectable by growth-based …
pathogens pose an increased health risk as they are undetectable by growth-based …
Active lysogeny in Listeria monocytogenes is a bacteria-phage adaptive response in the mammalian environment
A Pasechnek, L Rabinovich, O Stadnyuk, G Azulay… - Cell Reports, 2020 - cell.com
Summary Some Listeria monocytogenes (Lm) strains harbor a prophage within the comK
gene, which renders it inactive. During Lm infection of macrophage cells, the prophage turns …
gene, which renders it inactive. During Lm infection of macrophage cells, the prophage turns …