[HTML][HTML] A spatial human thymus cell atlas mapped to a continuous tissue axis
T cells develop from circulating precursor cells, which enter the thymus and migrate through
specialized subcompartments that support their maturation and selection. In humans, this …
specialized subcompartments that support their maturation and selection. In humans, this …
Rediscovering the human thymus through cutting-edge technologies
F Pala, LD Notarangelo, M Bosticardo - Journal of Experimental …, 2024 - rupress.org
Recent technological advances have transformed our understanding of the human thymus.
Innovations such as high-resolution imaging, single-cell omics, and organoid cultures …
Innovations such as high-resolution imaging, single-cell omics, and organoid cultures …
[HTML][HTML] Rebuilding and rebooting immunity with stem cells
LN Stankiewicz, FMV Rossi, PW Zandstra - Cell Stem Cell, 2024 - cell.com
Advances in modern medicine have enabled a rapid increase in lifespan and, consequently,
have highlighted the immune system as a key driver of age-related disease. Immune …
have highlighted the immune system as a key driver of age-related disease. Immune …
The Proteostasis of Thymic Stromal Cells in Health and Diseases
T Liu, S Xia - The Protein Journal, 2024 - Springer
The thymus is the key immune organ for the development of T cells. Different populations of
thymic stromal cells interact with T cells, thereby controlling the dynamic development of T …
thymic stromal cells interact with T cells, thereby controlling the dynamic development of T …
[PDF][PDF] A pipeline for discovery-based research on human T cell development: integrating spatial omics and PSC-T cell platforms
L Stankiewicz - 2024 - open.library.ubc.ca
T cells play a critical role in adaptive immunity by recognizing self, versus non-self antigens,
effectively protecting against pathogens and damaged or cancerous body cells. The …
effectively protecting against pathogens and damaged or cancerous body cells. The …