Older adult participation in cancer clinical trials: a systematic review of barriers and interventions
MS Sedrak, RA Freedman, HJ Cohen… - CA: a cancer journal …, 2021 - Wiley Online Library
Cancer is a disease of aging and, as the world's population ages, the number of older
persons with cancer is increasing and will make up a growing share of the oncology …
persons with cancer is increasing and will make up a growing share of the oncology …
Cancer and aging: two tightly interconnected biological processes
L Berben, G Floris, H Wildiers, S Hatse - Cancers, 2021 - mdpi.com
Simple Summary As life expectancy is increasing, the older population is rapidly growing.
However, older patients with cancer are still underrepresented in clinical trials, making …
However, older patients with cancer are still underrepresented in clinical trials, making …
Depression and anxiety in long-term survivors 5 and 10 years after cancer diagnosis
H Götze, M Friedrich, S Taubenheim, A Dietz… - Supportive Care in …, 2020 - Springer
Purpose Our study provides data on depression and anxiety in long-term cancer survivors,
in men, women and various age groups, as well as identifies associated factors and coping …
in men, women and various age groups, as well as identifies associated factors and coping …
Gait speed, grip strength, and clinical outcomes in older patients with hematologic malignancies
MA Liu, C DuMontier, A Murillo… - Blood, The Journal …, 2019 - ashpublications.org
This study aimed to evaluate whether gait speed and grip strength predicted clinical
outcomes among older adults with blood cancers. We prospectively recruited 448 patients …
outcomes among older adults with blood cancers. We prospectively recruited 448 patients …
Obesity and cancer pathogenesis
NA Berger - Annals of the New York Academy of Sciences, 2014 - Wiley Online Library
Overweight and obesity have reached pandemic levels on a worldwide basis and are
associated with increased risk and worse prognosis for many but not all malignancies …
associated with increased risk and worse prognosis for many but not all malignancies …
What every oncologist should know about geriatric assessment for older patients with cancer: young international society of geriatric oncology position paper
KP Loh, E Soto-Perez-de-Celis, T Hsu… - Journal of oncology …, 2018 - ascopubs.org
Aging is a heterogeneous process. Most newly diagnosed cancers occur in older adults, and
it is important to understand a patient's underlying health status when making treatment …
it is important to understand a patient's underlying health status when making treatment …
Analyzing the determinants to accept a virtual assistant and use cases among cancer patients: a mixed methods study
MJP van Bussel, GJ Odekerken–Schröder… - BMC Health Services …, 2022 - Springer
Background Technological progress in artificial intelligence has led to the increasing
popularity of virtual assistants, ie, embodied or disembodied conversational agents that …
popularity of virtual assistants, ie, embodied or disembodied conversational agents that …
[HTML][HTML] Characterization of skin aging–associated secreted proteins (SAASP) produced by dermal fibroblasts isolated from intrinsically aged human skin
DMW Lupa, F Kalfalah, K Safferling, P Boukamp… - Journal of Investigative …, 2015 - Elsevier
Most molecular hallmarks of cellular senescence have been identified in studies of cells
aged in vitro by driving them into replicative or stress-induced senescence. Comparatively …
aged in vitro by driving them into replicative or stress-induced senescence. Comparatively …
The coincidence between increasing age, immunosuppression, and the incidence of patients with glioblastoma
E Ladomersky, DM Scholtens… - Frontiers in …, 2019 - frontiersin.org
Background: Glioblastoma (GBM) is the most aggressive primary brain tumor in adults and is
associated with a median overall survival (mOS) of 16–21 months. Our previous work found …
associated with a median overall survival (mOS) of 16–21 months. Our previous work found …
Endothelial transplantation rejuvenates aged hematopoietic stem cell function
MG Poulos, P Ramalingam, MC Gutkin… - The Journal of …, 2017 - Am Soc Clin Investig
Age-related changes in the hematopoietic compartment are primarily attributed to cell-
intrinsic alterations in hematopoietic stem cells (HSCs); however, the contribution of the …
intrinsic alterations in hematopoietic stem cells (HSCs); however, the contribution of the …