Emergence of Oropouche fever in Latin America: a narrative review

KM Wesselmann, I Postigo-Hidalgo, L Pezzi… - The Lancet Infectious …, 2024 - thelancet.com
Since its discovery in 1955, the incidence and geographical spread of reported Oropouche
virus (OROV) infections have increased. Oropouche fever has been suggested to be one of …

It's in the mix: Reassortment of segmented viral genomes

AC Lowen - PLoS Pathogens, 2018 - journals.plos.org
Segmentation of viral genomes allows exchange of intact genes between related viruses
when they coinfect the same cell (Fig 1). This exchange is a type of recombination called …

Baseline mapping of Oropouche virology, epidemiology, therapeutics, and vaccine research and development

MA Files, CA Hansen, VC Herrera, C Schindewolf… - npj Vaccines, 2022 - nature.com
Oropouche virus (OROV) is an arthropod-borne orthobunyavirus found in South America
and causes Oropouche fever, a febrile infection similar to dengue. It is the second most …

[HTML][HTML] Hybrid gene origination creates human-virus chimeric proteins during infection

JSY Ho, M Angel, Y Ma, E Sloan, G Wang… - Cell, 2020 - cell.com
RNA viruses are a major human health threat. The life cycles of many highly pathogenic
RNA viruses like influenza A virus (IAV) and Lassa virus depends on host mRNA, because …

Oropouche virus glycoprotein topology and cellular requirements for glycoprotein secretion

NS Barbosa, JO Concha, LLP Dasilva… - Journal of …, 2023 - Am Soc Microbiol
Oropouche virus (OROV; genus Orthobunyavirus) is the etiological agent of Oropouche
fever, a debilitating febrile illness common in South America. We used recombinant …

Structure, function, and evolution of the Orthobunyavirus membrane fusion glycoprotein

J Hellert, A Aebischer, A Haouz, P Guardado-Calvo… - Cell Reports, 2023 - cell.com
La Crosse virus, responsible for pediatric encephalitis in the United States, and
Schmallenberg virus, a highly teratogenic veterinary virus in Europe, belong to the large …

Recent advances in Bunyavirus reverse genetics research: systems development, applications, and future perspectives

F Ren, S Shen, Q Wang, G Wei, C Huang… - Frontiers in …, 2021 - frontiersin.org
Bunyaviruses are members of the Bunyavirales order, which is the largest group of RNA
viruses, comprising 12 families, including a large group of emerging and re-emerging …

Emergent Arboviruses: A Review About Mayaro virus and Oropouche orthobunyavirus

TN Pereira, F Virginio, JI Souza… - Frontiers in Tropical …, 2021 - frontiersin.org
Arthropod-borne viruses have a significant impact on public health worldwide, and their (re)
emergence put aside the importance of other circulating arboviruses. Therefore, this scoping …

Bluetongue research at a crossroads: Modern genomics tools can pave the way to new insights

J Kopanke, M Carpenter, J Lee, K Reed… - Annual Review of …, 2022 - annualreviews.org
Bluetongue virus (BTV) is an arthropod-borne, segmented double-stranded RNA virus that
can cause severe disease in both wild and domestic ruminants. BTV evolves via several key …

M Segment-Based Minigenomes and Virus-Like Particle Assays as an Approach To Assess the Potential of Tick-Borne Phlebovirus Genome Reassortment

VV Rezelj, TJ Mottram, J Hughes, RM Elliott… - Journal of …, 2019 - Am Soc Microbiol
Bunyaviruses have a tripartite negative-sense RNA genome. Due to the segmented nature
of these viruses, if two closely related viruses coinfect the same host or vector cell, it is …