Neurotrophic Keratopathy (NK) refers to a condition where corneal epitheliopathy leading to
frank epithelial defect with or without stromal ulceration (melting) is associated with reduced …

An important component of tissue engineering (TE) is the supporting matrix upon which cells
and tissues grow, also known as the scaffold. Scaffolds must easily integrate with host tissue …

The amniotic membrane is the innermost of the three layers forming the fetal membranes. It
was first used in 1910 in skin transplantation. Thereafter it has been used in surgical …

Materials and Methods This is a prospective, interventional, consecutive case series
conducted at Careggi Hospital affiliated with Florence University School of Medicine. All the …

Persistent corneal epithelial defects (PEDs or PCEDs) result from the failure of rapid re-
epithelialization and closure within 10-14 days after a corneal injury, even with standard …

Chemical injuries frequently result in vision loss, disfigurement, and challenging ocular
surface complications. Acute interventions are directed at decreasing the extent of the injury …

The corneal epithelium is continuously renewed by limbal stem/progenitor cells (LSCs), a
cell population harbored in a highly regulated niche located at the limbus. Dysfunction …

Ocular burns constitute true ocular emergencies and both thermal and chemical burns
represent potentially blinding ocular injuries. Thermal burns result from accidents associated …

In 1910 Davis was the first to report the use of fetal membranes as surgical material in skin
transplantation. 1 Since then the use of amniotic membrane in surgery has been expanded …

In acute burns, amniotic membrane transplantation can be considered as an early, if not
immediate, surgical procedure to promote epithelialization and suppress inflammation so …