One leading hypothesis suggests that memories are stored in ensembles of neurons (or
'engram cells') and that successful recall involves reactivation of these ensembles. A logical …

Over the past century, psychologists have discussed whether forgetting might arise from
active mechanisms that promote memory loss to achieve various functions, such as …

Importance Childhood maltreatment is associated with mental illness. Researchers,
clinicians, and public health professionals use prospective or retrospective measures …

A new theory about the origins of consciousness that finds learning to be the driving force in
the evolutionary transition to basic consciousness. What marked the evolutionary transition …

Advancements in novel neurotechnologies, such as brain computer interfaces (BCI) and
neuromodulatory devices such as deep brain stimulators (DBS), will have profound …

The predominant focus in the neurobiological study of memory has been on remembering
(persistence). However, recent studies have considered the neurobiology of forgetting …

Pioneering research studies, beginning with those using Drosophila, have identified several
molecular and cellular mechanisms for active forgetting. The currently known mechanisms …

Retrieval-mediated learning is a powerful way to make memories last, but its neurocognitive
mechanisms remain unclear. We propose that retrieval acts as a rapid consolidation event …

Abstract Analysis methods in cognitive neuroscience have not always matched the richness
of fMRI data. Early methods focused on estimating neural activity within individual voxels or …

Memories play a ubiquitous role in our emotional lives, both causing vivid emotional
experiences in their own right and imbuing perception of the external world with emotional …