BCS class IV drugs: Highly notorious candidates for formulation development

R Ghadi, N Dand - Journal of Controlled Release, 2017 - Elsevier
BCS class IV drugs (eg, amphotericin B, furosemide, acetazolamide, ritonavir, paclitaxel)
exhibit many characteristics that are problematic for effective oral and per oral delivery …

Stability of nanosuspensions in drug delivery

Y Wang, Y Zheng, L Zhang, Q Wang… - Journal of controlled …, 2013 - Elsevier
Nanosuspensions are nanosized colloidal dispersion systems that are stabilized by
surfactants and/or polymers. Because nanosizing results in the creation of new interfaces …

Design of biocompatible dendrimers for cancer diagnosis and therapy: current status and future perspectives

Y Cheng, L Zhao, Y Li, T Xu - Chemical Society Reviews, 2011 - pubs.rsc.org
In the past decade, nanomedicine with its promise of improved therapy and diagnostics has
revolutionized conventional health care and medical technology. Dendrimers and dendrimer …

Drug nanocrystals: Fabrication methods and promising therapeutic applications

IS Mohammad, H Hu, L Yin, W He - International journal of pharmaceutics, 2019 - Elsevier
The drug nanocrystals (NCs) with unique physicochemical properties are now considered
as a promising drug delivery system for poorly water-soluble drugs. So far> 20 formulations …

Chitosan nanoparticles prepared by ionotropic gelation: An overview of recent advances

KG Desai - Critical Reviews™ in Therapeutic Drug Carrier …, 2016 - dl.begellhouse.com
The objective of this review is to summarize recent advances in chitosan nanoparticles
prepared by ionotropic gelation. Significant progress has occurred in this area since the …

Nanoparticulate delivery systems for antiviral drugs

D Lembo, R Cavalli - Antiviral Chemistry and Chemotherapy, 2010 - journals.sagepub.com
Nanomedicine opens new therapeutic avenues for attacking viral diseases and for
improving treatment success rates. Nanoparticulate-based systems might change the …

Non-sink dissolution conditions for predicting product quality and in vivo performance of supersaturating drug delivery systems

DD Sun, H Wen, LS Taylor - Journal of pharmaceutical sciences, 2016 - Elsevier
With recent advances in the development of supersaturating oral dosage forms for poorly
water-soluble drugs, pharmaceutical scientists are increasingly applying in vitro dissolution …

Identifying the correlation between drug/stabilizer properties and critical quality attributes (CQAs) of nanosuspension formulation prepared by wet media milling …

M George, I Ghosh - European Journal of Pharmaceutical Sciences, 2013 - Elsevier
Wet media milling by top down method has proved to be an effective method to prepare
nanosuspension of poorly soluble drugs/APIs. Few or no attempts have been made so far to …

Dissolution studies of poorly soluble drug nanosuspensions in non-sink conditions

P Liu, O De Wulf, J Laru, T Heikkilä, B van Veen… - Aaps Pharmscitech, 2013 - Springer
Sink conditions used in dissolution tests lead to rapid dissolution rates for nanosuspensions,
causing difficulties in discriminating dissolution profiles between different formulations. Here …

Nanotechnology and the treatment of HIV infection

R Parboosing, GEM Maguire, P Govender, HG Kruger - Viruses, 2012 - mdpi.com
Suboptimal adherence, toxicity, drug resistance and viral reservoirs make the lifelong
treatment of HIV infection challenging. The emerging field of nanotechnology may play an …