BCS class IV drugs: Highly notorious candidates for formulation development
BCS class IV drugs (eg, amphotericin B, furosemide, acetazolamide, ritonavir, paclitaxel)
exhibit many characteristics that are problematic for effective oral and per oral delivery …
exhibit many characteristics that are problematic for effective oral and per oral delivery …
Stability of nanosuspensions in drug delivery
Y Wang, Y Zheng, L Zhang, Q Wang… - Journal of controlled …, 2013 - Elsevier
Nanosuspensions are nanosized colloidal dispersion systems that are stabilized by
surfactants and/or polymers. Because nanosizing results in the creation of new interfaces …
surfactants and/or polymers. Because nanosizing results in the creation of new interfaces …
Design of biocompatible dendrimers for cancer diagnosis and therapy: current status and future perspectives
Y Cheng, L Zhao, Y Li, T Xu - Chemical Society Reviews, 2011 - pubs.rsc.org
In the past decade, nanomedicine with its promise of improved therapy and diagnostics has
revolutionized conventional health care and medical technology. Dendrimers and dendrimer …
revolutionized conventional health care and medical technology. Dendrimers and dendrimer …
Drug nanocrystals: Fabrication methods and promising therapeutic applications
IS Mohammad, H Hu, L Yin, W He - International journal of pharmaceutics, 2019 - Elsevier
The drug nanocrystals (NCs) with unique physicochemical properties are now considered
as a promising drug delivery system for poorly water-soluble drugs. So far> 20 formulations …
as a promising drug delivery system for poorly water-soluble drugs. So far> 20 formulations …
Chitosan nanoparticles prepared by ionotropic gelation: An overview of recent advances
KG Desai - Critical Reviews™ in Therapeutic Drug Carrier …, 2016 - dl.begellhouse.com
The objective of this review is to summarize recent advances in chitosan nanoparticles
prepared by ionotropic gelation. Significant progress has occurred in this area since the …
prepared by ionotropic gelation. Significant progress has occurred in this area since the …
Nanoparticulate delivery systems for antiviral drugs
D Lembo, R Cavalli - Antiviral Chemistry and Chemotherapy, 2010 - journals.sagepub.com
Nanomedicine opens new therapeutic avenues for attacking viral diseases and for
improving treatment success rates. Nanoparticulate-based systems might change the …
improving treatment success rates. Nanoparticulate-based systems might change the …
Non-sink dissolution conditions for predicting product quality and in vivo performance of supersaturating drug delivery systems
With recent advances in the development of supersaturating oral dosage forms for poorly
water-soluble drugs, pharmaceutical scientists are increasingly applying in vitro dissolution …
water-soluble drugs, pharmaceutical scientists are increasingly applying in vitro dissolution …
Identifying the correlation between drug/stabilizer properties and critical quality attributes (CQAs) of nanosuspension formulation prepared by wet media milling …
M George, I Ghosh - European Journal of Pharmaceutical Sciences, 2013 - Elsevier
Wet media milling by top down method has proved to be an effective method to prepare
nanosuspension of poorly soluble drugs/APIs. Few or no attempts have been made so far to …
nanosuspension of poorly soluble drugs/APIs. Few or no attempts have been made so far to …
Dissolution studies of poorly soluble drug nanosuspensions in non-sink conditions
P Liu, O De Wulf, J Laru, T Heikkilä, B van Veen… - Aaps Pharmscitech, 2013 - Springer
Sink conditions used in dissolution tests lead to rapid dissolution rates for nanosuspensions,
causing difficulties in discriminating dissolution profiles between different formulations. Here …
causing difficulties in discriminating dissolution profiles between different formulations. Here …
Nanotechnology and the treatment of HIV infection
Suboptimal adherence, toxicity, drug resistance and viral reservoirs make the lifelong
treatment of HIV infection challenging. The emerging field of nanotechnology may play an …
treatment of HIV infection challenging. The emerging field of nanotechnology may play an …