SUMMARY Herpes simplex virus 2 (HSV-2) is a DNA virus that is efficiently transmitted
through intimate genital tract contact and causes persistent infection that cannot be …

Genital herpes is a relatively common infection caused by herpes simplex virus (HSV) type
one or two (HSV-1, HSV-2) respectively. It is acquired most commonly via sexual activity …

Skin disease due to viruses may be a primary infection of the epidermis or may arise
secondary to systemic infection. Depending on the virus, the effects may be necrotic damage …

Background A 2017 systematic review and meta-analysis of 55 prospective studies found
the adjusted risk of HIV acquisition to be at least tripled in individuals with herpes simplex …

Background Pritelivir, an inhibitor of the viral helicase–primase complex, exhibits antiviral
activity in vitro and in animal models of herpes simplex virus (HSV) infection. We tested the …

Abstract Herpes simplex virus-2 (HSV-2) is periodically shed throughout the human genital
tract. Although a high viral load correlates with the development of genital ulcers, shedding …

Highlights•We review the current state of anti-HSV chemotherapy, including resistance
rates.•We highlight novel agents under investigation for the treatment of HSV …

In the present study, the antiviral properties of the bacteriocin subtilosin against Herpes
simplex virus type 1 (HSV-1) and the safety and efficacy of a subtilosin-based nanofiber …

Importance Current therapy of herpes infections relies on nucleoside analogues. Pritelivir is
a well-tolerated novel herpes simplex virus (HSV) helicase-primase inhibitor that reduced …

Genital herpes (GH) is caused by 2 related yet distinct viruses: herpes simplex viruses (HSV)
type-1 (HSV-1) and type-2 (HSV-2). 1 In 2016, there were an estimated 491.5 million people …