The rapid evolution and dissemination of antibiotic resistance among bacterial pathogens
are outpacing the development of new antibiotics, but antivirulence agents provide an …

Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, an infectious
disease with one of the highest morbidity and mortality rates worldwide. Leveraging its …

The Mycobacterium tuberculosis complex (MTBC) consists of closely related species that
cause tuberculosis in both humans and animals. This illness, still today, remains to be one of …

Tuberculosis (TB), one of the oldest known human diseases. is still is one of the major
causes of mortality, since two million people die each year from this malady. TB has many …

In this review we discuss recent progress in the development, testing, and clinical evaluation
of new vaccines against tuberculosis (TB). Over the last 20 years, tremendous progress has …

During the past decade, there has been a paradigm shift in our understanding of the roles of
intracellular lipid droplets (LDs). New genetic, biochemical and imaging technologies have …

Tuberculosis (TB) is the leading cause of infectious death worldwide. Development of
improved TB vaccines that boost or replace BCG is a major global health goal. ID93+ GLA …

Global spread and limited genetic variation are hallmarks of M. tuberculosis, the agent of
human tuberculosis. In contrast, Mycobacterium canettii and related tubercle bacilli that also …

Antibody-based therapies are currently undergoing a renaissance. After being developed
and then largely abandoned in the twentieth century, many antibody preparations are now in …

Mycobacterium tuberculosis, the etiological agent of tuberculosis (TB), is an extremely
successful pathogen that adapts to survive within the host. During the latency phase of …