The role of epidemic resistance plasmids and international high-risk clones in the spread of multidrug-resistant Enterobacteriaceae

AJ Mathers, G Peirano, JDD Pitout - Clinical microbiology reviews, 2015 - Am Soc Microbiol
Escherichia coli sequence type 131 (ST131) and Klebsiella pneumoniae ST258 emerged in
the 2000s as important human pathogens, have spread extensively throughout the world …

Fecal Colonization With Extended-spectrum Beta-lactamase–Producing Enterobacteriaceae and Risk Factors Among Healthy Individuals: A Systematic Review and …

S Karanika, T Karantanos, M Arvanitis… - Reviews of Infectious …, 2016 - academic.oup.com
Background. Gut colonization is a risk factor for infections with extended-spectrum beta-
lactamase (ESBL)–producing organisms. We aimed to determine the ESBL class A reservoir …

Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America

HW Boucher, GH Talbot, JS Bradley… - Clinical infectious …, 2009 - academic.oup.com
Abstract The Infectious Diseases Society of America (IDSA) continues to view with concern
the lean pipeline for novel therapeutics to treat drug-resistant infections, especially those …

Impact of multidrug-resistant Pseudomonas aeruginosa infection on patient outcomes

EB Hirsch, VH Tam - Expert review of pharmacoeconomics & …, 2010 - Taylor & Francis
Rates of antibiotic resistance in Pseudomonas aeruginosa are increasing worldwide. The
multidrug-resistant (MDR) phenotype in P. aeruginosa could be mediated by several …

[HTML][HTML] Economic burden of antibiotic resistance: how much do we really know?

S Gandra, DM Barter, R Laxminarayan - Clinical microbiology and infection, 2014 - Elsevier
The declining effectiveness of antibiotics imposes potentially large health and economic
burdens on societies. Quantifying the economic outcomes of antibiotic resistance effectively …

Clinical and economic impact of common multidrug-resistant gram-negative bacilli

CG Giske, DL Monnet, O Cars… - Antimicrobial agents and …, 2008 - Am Soc Microbiol
During the last decade, the efforts to combat multidrugresistant (MDR) microorganisms
mainly focused on gram-positive bacteria, namely, methicillin-resistant Staphylococcus …

Mortality and delay in effective therapy associated with extended-spectrum β-lactamase production in Enterobacteriaceae bacteraemia: a systematic review and meta …

MJ Schwaber, Y Carmeli - Journal of Antimicrobial …, 2007 - academic.oup.com
Objectives We performed a systematic review and meta-analysis to examine the impact of
extended-spectrum β-lactamase (ESBL) production on mortality and delay in effective …

[HTML][HTML] Infections with extended-spectrum β-lactamase-producing Enterobacteriaceae: changing epidemiology and drug treatment choices

JDD Pitout - Drugs, 2010 - Springer
Since 2000, Escherichia coli producing CTX-M enzymes (especially CTX-M-15) have
emerged worldwide as important causes of community-onset urinary tract infections (UTIs) …

Antimicrobials Increase Travelers' Risk of Colonization by Extended-Spectrum Betalactamase-Producing Enterobacteriaceae

A Kantele, T Lääveri, S Mero, K Vilkman… - Clinical Infectious …, 2015 - academic.oup.com
Background. More than 300 million travelers visit regions with poor hygiene annually. A
significant percentage of them become colonized by resistant intestinal bacteria such as …

Molecular epidemiology of Escherichia coli producing CTX-M β-lactamases: the worldwide emergence of clone ST131 O25: H4

G Peirano, JDD Pitout - International journal of antimicrobial agents, 2010 - Elsevier
Since 2000, Escherichia coli producing CTX-M enzymes have emerged worldwide as
important causes of community-onset urinary tract and bloodstream infections owing to …