[HTML][HTML] Impacts of exercise interventions on different diseases and organ functions in mice
S Guo, Y Huang, Y Zhang, H Huang, S Hong… - Journal of sport and health …, 2020 - Elsevier
Background In recent years, much evidence has emerged to indicate that exercise can
benefit people when performed properly. This review summarizes the exercise interventions …
benefit people when performed properly. This review summarizes the exercise interventions …
Treatment of AML relapse after allo-HCT
JA Webster, L Luznik, I Gojo - Frontiers in Oncology, 2021 - frontiersin.org
With advances in allogeneic hematopoietic stem cell transplant (allo-HCT), disease relapse
has replaced transplant-related mortality as the primary cause of treatment failure for …
has replaced transplant-related mortality as the primary cause of treatment failure for …
Pediatric multicellular tumor spheroid models illustrate a therapeutic potential by combining BH3 mimetics with Natural Killer (NK) cell-based immunotherapy
V Särchen, S Shanmugalingam, S Kehr… - Cell death …, 2022 - nature.com
The induction of apoptosis is a direct way to eliminate tumor cells and improve cancer
therapy. Apoptosis is tightly controlled by the balance of pro-and antiapoptotic Bcl-2 …
therapy. Apoptosis is tightly controlled by the balance of pro-and antiapoptotic Bcl-2 …
BH3 mimetics in AML therapy: death and beyond?
B cell lymphoma 2 (BCL2) homology domain 3 (BH3) mimetics are targeted therapeutic
agents that allow response prediction and patient stratification. BH3 mimetics are …
agents that allow response prediction and patient stratification. BH3 mimetics are …
Smart Conditioning with Venetoclax-Enhanced Sequential FLAMSA+ RIC in Patients with High-Risk Myeloid Malignancies
F Schulz, P Jäger, J Tischer, A Fraccaroli, G Bug… - Cancers, 2024 - mdpi.com
Simple Summary Allogeneic stem cell transplantation (aHSCT) is the only potentially
curative treatment option for patients with high-risk myeloid malignancies. Depending on the …
curative treatment option for patients with high-risk myeloid malignancies. Depending on the …
Hematopoietic stem cell transplantation for acute myeloid leukemia: an overview of systematic reviews
P He, J Liang, W Zhang, S Lin, H Wu… - … Journal of Clinical …, 2022 - Wiley Online Library
Background. Hematopoietic stem cell transplantation (HSCT) has become the main
treatment for acute myeloid leukemia (AML) and has been studied in many systematic …
treatment for acute myeloid leukemia (AML) and has been studied in many systematic …
Emerging roles of the HECT-type E3 ubiquitin ligases in hematological malignancies
VS Delvecchio, C Fierro, S Giovannini, G Melino… - Discover Oncology, 2021 - Springer
Ubiquitination-mediated proteolysis or regulation of proteins, ultimately executed by E3
ubiquitin ligases, control a wide array of cellular processes, including transcription, cell …
ubiquitin ligases, control a wide array of cellular processes, including transcription, cell …
Venetoclax or ruxolitinib in pre-transplant conditioning lowers the engraftment barrier by different mechanisms in allogeneic stem cell transplant recipients
JE Davis, K Du, MJ Ludford-Menting… - Frontiers in …, 2021 - frontiersin.org
Allogeneic stem cell transplantation (alloSCT) is utilised to cure haematological
malignancies through a combination of conditioning regimen intensity and immunological …
malignancies through a combination of conditioning regimen intensity and immunological …
[HTML][HTML] Anti-apoptotic molecule BCL2 is a therapeutic target in steroid-refractory graft-versus-host disease
J Strobl, RV Pandey, T Krausgruber, L Kleissl… - Journal of Investigative …, 2020 - Elsevier
Graft-versus-host disease (GVHD) is the leading cause of mortality after hematopoietic stem
cell transplantation and primarily affects barrier organs such as the skin. One-third of cases …
cell transplantation and primarily affects barrier organs such as the skin. One-third of cases …
[HTML][HTML] 维奈克拉, 地西他滨及改良HA 方案联合供者淋巴细胞输注治疗儿童造血干细胞移植后复发AML/MDS 的安全性和有效性研究
张枫, 王慧芳, 胡冠华, 锁盼, 柏露… - Chinese Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
目的探究急性髓系白血病(AML)/骨髓增生异常综合征(MDS) 患儿异基因造血干细胞移植(allo-
HSCT) 后分子学复发及血液学复发者, 应用维奈克拉联合地西他滨, 阿糖胞苷 …
HSCT) 后分子学复发及血液学复发者, 应用维奈克拉联合地西他滨, 阿糖胞苷 …