RNA interference (RNAi) is a powerful approach for reducing expression of endogenously
expressed proteins. It is widely used for biological applications and is being harnessed to …

MicroRNAs (miRNAs) are a kind of conserved small non-coding RNAs that participate in
regulating gene expression by targeting multiple molecules. Early studies have shown that …

Short hairpin RNA (shRNA) technology enables stable and regulated gene repression. For
establishing experimentally versatile RNAi tools and minimizing toxicities, synthetic shRNAs …

Plant microRNAs (miRNAs) regulate the abundance of target mRNAs by guiding their
cleavage at the sequence complementary region. We have modified an Arabidopsis …

MicroRNAs (miRNAs) are 21–24 nucleotide (nt) duplex RNAs that are created from
precursor transcripts by subsequent processing steps mediated by members of the RNAseIII …

RNA interference is a powerful method for suppressing gene expression in mammalian
cells. Stable knock-down can be achieved by continuous expression of synthetic short …

ABSTRACT RNA silencing in plants is a natural defense system against foreign genetic
elements including viruses. This natural antiviral mechanism has been adopted to develop …

In recent years, various rna-based technologies have been under evaluation as potential
next-generation cancer therapeutics. Micrornas (mirnas), known to regulate the cell cycle …

An efficient mechanism for the sequence‐specific inhibition of gene expression is RNA
interference. In this process, double‐stranded RNA molecules induce cleavage of a selected …

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