Multidrug-resistant Acinetobacter baumannii as an emerging concern in hospitals

S Ibrahim, N Al-Saryi, IMS Al-Kadmy, SN Aziz - Molecular biology reports, 2021 - Springer
Acinetobacter baumannii has become a major concern for scientific attention due to
extensive antimicrobial resistance. This resistance causes an increase in mortality rate …

Nanotechnology as a promising approach to combat multidrug resistant bacteria: a comprehensive review and future perspectives

HF Hetta, YN Ramadan, AI Al-Harbi, E A. Ahmed… - Biomedicines, 2023 - mdpi.com
The wide spread of antibiotic resistance has been alarming in recent years and poses a
serious global hazard to public health as it leads to millions of deaths all over the world. The …

Current update on intrinsic and acquired colistin resistance mechanisms in bacteria

FA Gogry, MT Siddiqui, I Sultan, QMR Haq - Frontiers in medicine, 2021 - frontiersin.org
Colistin regained global interest as a consequence of the rising prevalence of multidrug-
resistant Gram-negative Enterobacteriaceae. In parallel, colistin-resistant bacteria emerged …

Mobilized colistin resistance (mcr) genes from 1 to 10: a comprehensive review

NH Hussein, IMS Al-Kadmy, BM Taha… - Molecular biology …, 2021 - Springer
At the present time, the polymyxin antibiotic colistin is considered a last-line treatment option
for severe human infections caused by multi-drug and carbapenem-resistant Gram-negative …

Epidemiology of mobile colistin resistance genes mcr-1 to mcr-9

Z Ling, W Yin, Z Shen, Y Wang, J Shen… - Journal of …, 2020 - academic.oup.com
The identification of the first mobile colistin resistance (MCR) gene, mcr-1, in 2015 triggered
a rash of mcr screening reports. Subsequently, nine MCR-family genes and their variants …

Colistin Resistance in Acinetobacter baumannii: Molecular Mechanisms and Epidemiology

K Novović, B Jovčić - Antibiotics, 2023 - mdpi.com
Acinetobacter baumannii is recognized as a clinically significant pathogen causing a wide
spectrum of nosocomial infections. Colistin was considered a last-resort antibiotic for the …

Antibiofilm and antivirulence potential of silver nanoparticles against multidrug-resistant Acinetobacter baumannii

HF Hetta, IMS Al-Kadmy, SS Khazaal, S Abbas… - Scientific reports, 2021 - nature.com
We aimed to isolate Acinetobacter baumannii (A. baumannii) from wound infections,
determine their resistance and virulence profile, and assess the impact of Silver …

Progress and prospects of nanomaterials against resistant bacteria

J He, M Hong, W Xie, Z Chen, D Chen, S Xie - Journal of Controlled …, 2022 - Elsevier
Drug-resistant bacterial infections are increasingly heightening, which lead to more severe
illness, higher cost of treatment and increased risk of death. Nanomaterials-based therapy …

Acinetobacter baumannii in the critically ill: complex infections get complicated

I Cavallo, A Oliva, R Pages, F Sivori, M Truglio… - Frontiers in …, 2023 - frontiersin.org
Acinetobacter baumannii is increasingly associated with various epidemics, representing a
serious concern due to the broad level of antimicrobial resistance and clinical …

Detection of gyrA and parC Mutations and Prevalence of Plasmid-Mediated Quinolone Resistance Genes in Klebsiella pneumoniae

SM Kareem, IMS Al-Kadmy, SS Kazaal… - Infection and drug …, 2021 - Taylor & Francis
Background and Aim Recently, the extensive use of quinolones led to increased resistance
to these antimicrobial agents, with different rates according to the organism and the …