MR Imaging of Human Brain Mechanics In Vivo: New Measurements to Facilitate the Development of Computational Models of Brain Injury

PV Bayly, A Alshareef, AK Knutsen, K Upadhyay… - Annals of biomedical …, 2021 - Springer
Computational models of the brain and its biomechanical response to skull accelerations
are important tools for understanding and predicting traumatic brain injuries (TBIs) …

Magnetic resonance imaging of the pulsing brain: a systematic review

A Almudayni, M Alharbi, A Chowdhury, J Ince… - … Resonance Materials in …, 2023 - Springer
Objective To perform a systematic review of the literature exploring magnetic resonance
imaging (MRI) methods for measuring natural brain tissue pulsations (BTPs) in humans …

[HTML][HTML] Cardiac and respiration-induced brain deformations in humans quantified with high-field MRI

JJ Sloots, GJ Biessels, JJM Zwanenburg - Neuroimage, 2020 - Elsevier
Microvascular blood volume pulsations due to the cardiac and respiratory cycles induce
brain tissue deformation and, as such, are considered to drive the brain's waste clearance …

[HTML][HTML] Polytopal discontinuous Galerkin discretization of brain multiphysics flow dynamics

I Fumagalli, M Corti, N Parolini, PF Antonietti - Journal of Computational …, 2024 - Elsevier
A comprehensive mathematical model of the multiphysics flow of blood and Cerebrospinal
Fluid (CSF) in the brain can be expressed as the coupling of a poromechanics system and …

Cerebellar and brainstem displacement measured with DENSE MRI in Chiari malformation following posterior fossa decompression surgery

MS Eppelheimer, BST Nwotchouang… - Radiology, 2021 - pubs.rsna.org
Background Posterior fossa decompression (PFD) surgery is a treatment for Chiari
malformation type I (CMI). The goals of surgery are to reduce cerebellar tonsillar crowding …

Human intracranial pulsatility during the cardiac cycle: a computational modelling framework

M Causemann, V Vinje, ME Rognes - Fluids and Barriers of the CNS, 2022 - Springer
Background Today's availability of medical imaging and computational resources set the
scene for high-fidelity computational modelling of brain biomechanics. The brain and its …

3D amplified MRI (aMRI)

I Terem, L Dang, A Champagne… - Magnetic …, 2021 - Wiley Online Library
Purpose Amplified MRI (aMRI) has been introduced as a new method of detecting and
visualizing pulsatile brain motion in 2D. Here, we improve aMRI by introducing a novel 3D …

Quantifying cardiac‐induced brain tissue expansion using DENSE

AL Adams, HJ Kuijf, MA Viergever… - NMR in …, 2019 - Wiley Online Library
Brain tissue undergoes viscoelastic deformation and volumetric strain as it expands over the
cardiac cycle due to blood volume changes within the underlying microvasculature …

[HTML][HTML] Development, calibration, and testing of 3D amplified MRI (aMRI) for the quantification of intrinsic brain motion

J Abderezaei, A Pionteck, I Terem, L Dang, M Scadeng… - Brain Multiphysics, 2021 - Elsevier
Microvascular blood volume pulsations, combined with CSF circulation result in subtle
deformation of the brain during each heartbeat. To visualize and quantify these small …

[HTML][HTML] Validating faster DENSE measurements of cardiac-induced brain tissue expansion as a potential tool for investigating cerebral microvascular pulsations

AL Adams, MA Viergever, PR Luijten, JJM Zwanenburg - Neuroimage, 2020 - Elsevier
Abstract Displacement Encoding with Stimulated Echoes (DENSE) has recently shown
potential for measuring cardiac-induced cerebral volumetric strain in the human brain. As …