Updated epidemiology of gastrointestinal cancers in East Asia

J Huang, DE Lucero-Prisno III, L Zhang, W Xu… - Nature Reviews …, 2023 - nature.com
Globally, gastrointestinal cancers represent more than one-fourth of all cancer incidence
and one-third of cancer-related mortality. Although there has been much progress in …

Diosgenin: an updated pharmacological review and therapeutic perspectives

P Semwal, S Painuli, T Abu-Izneid… - Oxidative medicine …, 2022 - Wiley Online Library
Plants including Rhizoma polgonati, Smilax china, and Trigonella foenum-graecum contain
a lot of diosgenin, a steroidal sapogenin. This bioactive phytochemical has shown high …

[HTML][HTML] The global burden of metabolic disease: Data from 2000 to 2019

NWS Chew, CH Ng, DJH Tan, G Kong, C Lin, YH Chin… - Cell Metabolism, 2023 - cell.com
Global estimates of prevalence, deaths, and disability-adjusted life years (DALYs) from the
Global Burden of Diseases, Injuries, and Risk Factors Study 2019 were examined for …

The global syndemic of metabolic diseases in the young adult population: A consortium of trends and projections from the Global Burden of Disease 2000–2019

B Chong, G Kong, K Shankar, HSJ Chew, C Lin, R Goh… - Metabolism, 2023 - Elsevier
Background A significant proportion of premature deaths globally are related to metabolic
diseases in young adults. We examined the global trends and mortality of metabolic …

Early-onset cancer in the gastrointestinal tract is on the rise—evidence and implications

I Ben-Aharon, HWM van Laarhoven, E Fontana… - Cancer discovery, 2023 - AACR
Epidemiologic data indicate a significant increase in the incidence of colorectal cancer in
younger populations in the past three decades. Moreover, recent evidence also …

[HTML][HTML] Interplay of oxidative stress, cellular communication and signaling pathways in cancer

MJ Iqbal, A Kabeer, Z Abbas, HA Siddiqui… - Cell Communication and …, 2024 - Springer
Cancer remains a significant global public health concern, with increasing incidence and
mortality rates worldwide. Oxidative stress, characterized by the production of reactive …

[HTML][HTML] Babao Dan alleviates gut immune and microbiota disorders while impacting the TLR4/MyD88/NF-кB pathway to attenuate 5-Fluorouracil-induced intestinal …

B Huang, M Gui, H An, J Shen, F Ye, Z Ni… - Biomedicine & …, 2023 - Elsevier
Adjuvant chemotherapy based on 5-fluorouracil (5-FU), such as FOLFOX, is suggested as a
treatment for gastrointestinal cancer. Yet, intestinal damage continues to be a prevalent side …

[HTML][HTML] Recent updates on anticancer mechanisms of polyphenols

E Sharma, DC Attri, P Sati, P Dhyani… - Frontiers in Cell and …, 2022 - frontiersin.org
In today's scenario, when cancer cases are increasing rapidly, anticancer herbal
compounds become imperative. Studies on the molecular mechanisms of action of …

[HTML][HTML] Anticancer Potential and Other Pharmacological Properties of Prunus armeniaca L.: An Updated Overview

D Kitic, B Miladinovic, M Randjelovic, A Szopa… - Plants, 2022 - mdpi.com
Prunus armeniaca L.(Rosaceae)-syn. Amygdalus armeniaca (L.) Dumort., Armeniaca
armeniaca (L.) Huth, Armeniaca vulgaris Lam is commonly known as the apricot tree. The …

[HTML][HTML] Global, regional, and national lifetime risks of developing and dying from gastrointestinal cancers in 185 countries: a population-based systematic analysis of …

S Wang, R Zheng, J Li, H Zeng, L Li, R Chen… - The Lancet …, 2024 - thelancet.com
Background Gastrointestinal cancers account for a quarter of the global cancer incidence
and a third of cancer-related deaths. We sought to estimate the lifetime risks of developing …