Sex differences in pediatric infectious diseases

M Muenchhoff, PJR Goulder - The Journal of infectious diseases, 2014 - academic.oup.com
The success of the immune response is finely balanced between, on the one hand, the need
to engage vigorously with, and clear, certain pathogens; and, on the other, the requirement …

Sex differences in obstructive sleep apnoea

MR Bonsignore, T Saaresranta… - European Respiratory …, 2019 - Eur Respiratory Soc
Obstructive sleep apnoea (OSA) and obstructive sleep apnoea/hypopnoea syndrome
(OSAHS) have long been considered predominantly male-related conditions. The clinical …

Role of sleep quality in the metabolic syndrome

D Koren, M Dumin, D Gozal - Diabetes, metabolic syndrome and …, 2016 - Taylor & Francis
Emerging evidence has assigned an important role to sleep as a modulator of metabolic
homeostasis. The impact of variations in sleep duration, sleep-disordered breathing, and …

Pathophysiology of adult obstructive sleep apnea

DJ Eckert, A Malhotra - Proceedings of the American thoracic …, 2008 - atsjournals.org
Obstructive sleep apnea (OSA) is a common disorder characterized by repetitive narrowing
or collapse of the pharyngeal airway during sleep. The disorder is associated with major …

Aging and sleep: physiology and pathophysiology

BA Edwards, DM O'Driscoll, A Ali… - … in respiratory and …, 2010 - thieme-connect.com
Aging effects on sleep are important to consider for the practicing pulmonologist due to the
increase in prevalence of major respiratory disorders as well as the normal changes that …

Pathophysiology of pediatric obstructive sleep apnea

ES Katz, CM D'Ambrosio - Proceedings of the American Thoracic …, 2008 - atsjournals.org
Sleep-disordered breathing is a common and serious cause of metabolic, cardiovascular,
and neurocognitive morbidity in children. The spectrum of obstructive sleep-disordered …

Anatomical determinants of upper airway collapsibility in obstructive sleep apnea: a systematic review and meta-analysis

PJ Hartfield, J Janczy, A Sharma, HA Newsome… - Sleep Medicine …, 2023 - Elsevier
Upper airway (UA) collapsibility is one of the key factors that determine the severity of
obstructive sleep apnea (OSA). Interventions for OSA are aimed at reducing UA …

Upper airway collapsibility is associated with obesity and hyoid position

PR Genta, F Schorr, DJ Eckert, E Gebrim, F Kayamori… - Sleep, 2014 - academic.oup.com
Abstract Study Objectives: Upper airway anatomy plays a major role in obstructive sleep
apnea (OSA) pathogenesis. An inferiorly displaced hyoid as measured by the mandibular …

Associations between adenotonsillar hypertrophy, age, and obesity in children with obstructive sleep apnea

KT Kang, CH Chou, WC Weng, PL Lee, WC Hsu - PloS one, 2013 - journals.plos.org
Objective To investigate the contributions of adenoid and tonsil size to childhood obstructive
sleep apnea (OSA) and the interactions between adenotonsillar hypertrophy, age, and …

Obstructive sleep apnea in children: relative contributions of body mass index and adenotonsillar hypertrophy

E Dayyat, L Kheirandish-Gozal, OS Capdevila… - Chest, 2009 - Elsevier
Background The obesity epidemic has prompted remarkable changes in the proportion of
obese children who are referred for habitual snoring. However, the contribution of obesity to …