Facile measurement of protein stability and folding kinetics using a nano differential scanning fluorimeter
G Chattopadhyay, R Varadarajan - Protein Science, 2019 - Wiley Online Library
With advancements in high‐throughput generation of phenotypic data on mutant proteins, it
has become important to individually characterize different proteins or their variants rapidly …
has become important to individually characterize different proteins or their variants rapidly …
Insights into kinetics of agitation-induced aggregation of hen lysozyme under heat and acidic conditions from various spectroscopic methods
A Chaari, C Fahy, A Chevillot-Biraud, M Rholam - PLoS One, 2015 - journals.plos.org
Protein misfolding and amyloid formation are an underlying pathological hallmark in a
number of prevalent diseases of protein aggregation ranging from Alzheimer's and …
number of prevalent diseases of protein aggregation ranging from Alzheimer's and …
(−)-Epicatechin gallate prevents alkali-salt mediated fibrillogenesis of hen egg white lysozyme
Green tea polyphenols (GTPs) are found to be potent inhibitors of amyloid fibril formation.
We report the effective inhibitory property of (−)-epicatechin gallate (ECG) during the alkali …
We report the effective inhibitory property of (−)-epicatechin gallate (ECG) during the alkali …
Extraction, purification, and investigation of the antibacterial potential of lysozyme isolated from the latex of Calotropis procera
S Muthu, V Gopal, ZK AL-Younis, AB Altemimi… - … Food Research and …, 2024 - Springer
Calotropis procera produces a latex used in traditional medicine because of its components
which are found to be biologically active. The latex of C. procera has many benefits such as …
which are found to be biologically active. The latex of C. procera has many benefits such as …
Structural changes of human serum albumin (HSA) in simulated microgravity
A Hekmat, Z Hajebrahimi… - Protein and peptide …, 2017 - ingentaconnect.com
Background: Nowadays, the biological effects of microgravity have been the subject of
various experimental researches. Microgravity has been confirmed to affect biological …
various experimental researches. Microgravity has been confirmed to affect biological …
Polyphenols protect mitochondrial membrane against permeabilization induced by HEWL oligomers: Possible mechanism of action
Increasing body of evidence suggests that polyphenols frequently interacting with amyloid
aggregates and/or interfering with aggregate species to bind biomembranes may serve as a …
aggregates and/or interfering with aggregate species to bind biomembranes may serve as a …
Interaction of gallium, indium and vanadyl diacetylcurcumin complexes with lysozyme: mechanistic aspects and evaluation of antiamyloidogenic activity
A Sahraei, A Ehsanfar… - Royal Society Open …, 2023 - royalsocietypublishing.org
Diacetylcurcumin as a derivative of curcumin is a strong nitric oxide (NO) and O2−. anion
scavenger. One strategy to improve stability of curcumin and its derivatives is complexation …
scavenger. One strategy to improve stability of curcumin and its derivatives is complexation …
A comparative study on the aggregating effects of guanidine thiocyanate, guanidine hydrochloride and urea on lysozyme aggregation
S Emadi, M Behzadi - Biochemical and biophysical research …, 2014 - Elsevier
Protein aggregation and its subsequent deposition in different tissues culminate in a diverse
range of diseases collectively known as amyloidoses. Aggregation of hen or human …
range of diseases collectively known as amyloidoses. Aggregation of hen or human …
Copper (II) directs formation of toxic amorphous aggregates resulting in inhibition of hen egg white lysozyme fibrillation under alkaline salt-mediated conditions
Hen egg white lysozyme (HEWL) adopts a molten globule-like state at high pH (~ 12.75) and
is found to form amyloid fibrils at alkaline pH. Here, we report that Cu (II) inhibits self …
is found to form amyloid fibrils at alkaline pH. Here, we report that Cu (II) inhibits self …
[HTML][HTML] Crowded milieu prevents fibrillation of hen egg white lysozyme with retention of enzymatic activity
Molten globule state plays a crucial role in the amyloidogenesis of several proteins. Hen egg
white lysozyme (HEWL) acquires a molten globule state at alkaline pH (12.75). Our study …
white lysozyme (HEWL) acquires a molten globule state at alkaline pH (12.75). Our study …