DNA nanostructure-based nucleic acid probes: construction and biological applications

DX Wang, J Wang, YX Wang, YC Du, Y Huang… - Chemical …, 2021 - pubs.rsc.org
In recent years, DNA has been widely noted as a kind of material that can be used to
construct building blocks for biosensing, in vivo imaging, drug development, and disease …

Graphene family in cancer therapy: recent progress in cancer gene/drug delivery applications

NB Moghadam, M Avatefi, M Karimi… - Journal of Materials …, 2023 - pubs.rsc.org
In the past few years, the development in the construction and architecture of graphene
based nanocomplexes has dramatically accelerated the use of nano-graphene for …

[HTML][HTML] Cardiomyocytes from human pluripotent stem cells: from laboratory curiosity to industrial biomedical platform

C Denning, V Borgdorff, J Crutchley, KSA Firth… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Cardiomyocytes from human pluripotent stem cells (hPSCs-CMs) could revolutionise
biomedicine. Global burden of heart failure will soon reach USD $90 bn, while unexpected …

Fluorescence in situ hybridization (FISH) and cell sorting of living bacteria

G Batani, K Bayer, J Böge, U Hentschel, T Thomas - Scientific reports, 2019 - nature.com
Despite the development of several cultivation methods, the rate of discovery of
microorganisms that are yet-to-be cultivated outpaces the rate of isolating and cultivating …

Lineage tracing reveals B cell antibody class switching is stochastic, cell-autonomous, and tuneable

MB Horton, HC Cheon, KR Duffy, D Brown, SH Naik… - Immunity, 2022 - cell.com
To optimize immunity to pathogens, B lymphocytes generate plasma cells with functionally
diverse antibody isotypes. By lineage tracing single cells within differentiating B cell clones …

Genetically modified pigs are protected from classical swine fever virus

Z Xie, D Pang, H Yuan, H Jiao, C Lu, K Wang… - PLoS …, 2018 - journals.plos.org
Classical swine fever (CSF) caused by classical swine fever virus (CSFV) is one of the most
detrimental diseases, and leads to significant economic losses in the swine industry. Despite …

Genes with 5′ terminal oligopyrimidine tracts preferentially escape global suppression of translation by the SARS-CoV-2 Nsp1 protein

S Rao, I Hoskins, T Tonn, PD Garcia, H Ozadam… - Rna, 2021 - rnajournal.cshlp.org
Viruses rely on the host translation machinery to synthesize their own proteins.
Consequently, they have evolved varied mechanisms to co-opt host translation for their …

Oncogene-targeting nanoprobes for early imaging detection of tumor

W Li, P Zhang, C Liu, Y Xu, Z Gan, L Kang… - Journal of …, 2023 - Springer
Malignant tumors have been one of the major reasons for deaths worldwide. Timely and
accurate diagnosis as well as effective intervention of tumors play an essential role in the …

An integrated flow cytometry-based platform for isolation and molecular characterization of circulating tumor single cells and clusters

N Bhagwat, K Dulmage, CH Pletcher Jr, L Wang… - Scientific reports, 2018 - nature.com
Comprehensive molecular analysis of rare circulating tumor cells (CTCs) and cell clusters is
often hampered by low throughput and purity, as well as cell loss. To address this, we …

Molecular beacon nano-sensors for probing living cancer cells

T Kuang, L Chang, X Peng, X Hu… - Trends in …, 2017 - cell.com
Heterogeneities and oncogenesis essentially result from proteomic disorders orchestrated
by changes in DNA and/or cytoplasmic mRNA. These genetic fluctuations, however, cannot …