Autoantibodies in systemic lupus erythematosus: From immunopathology to therapeutic target

H Lou, GS Ling, X Cao - Journal of autoimmunity, 2022 - Elsevier
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multiple
organ inflammatory damage and wide spectrum of autoantibodies. The autoantibodies …

Cutaneous lupus erythematosus: new insights into pathogenesis and therapeutic strategies

J Wenzel - Nature Reviews Rheumatology, 2019 - nature.com
Cutaneous lupus erythematosus (CLE) is an autoimmune disease that can present as an
isolated skin disease or as a manifestation within the spectrum of systemic lupus …

[HTML][HTML] Anti-double stranded DNA antibodies: origin, pathogenicity, and targeted therapies

X Wang, Y Xia - Frontiers in immunology, 2019 - frontiersin.org
Systemic lupus erythematosus (SLE) is characterized by high-titer serological
autoantibodies, including antibodies that bind to double-stranded DNA (dsDNA). The origin …

[HTML][HTML] Cutaneous lupus erythematosus: an update on pathogenesis and future therapeutic directions

D Niebel, L de Vos, T Fetter, C Brägelmann… - American Journal of …, 2023 - Springer
Lupus erythematosus comprises a spectrum of autoimmune diseases that may affect various
organs (systemic lupus erythematosus [SLE]) or the skin only (cutaneous lupus …

[HTML][HTML] Diagnostic utility of separate anti-Ro60 and anti-Ro52/TRIM21 antibody detection in autoimmune diseases

A Robbins, M Hentzien, S Toquet, K Didier… - Frontiers in …, 2019 - frontiersin.org
Anti-SS-A antibodies are often sought for in autoimmune diseases diagnosis. Two different
target proteins have actually been identified: Ro52 and Ro60. Clinical and immunological …

[HTML][HTML] BP180 is critical in the autoimmunity of bullous pemphigoid

Y Liu, L Li, Y Xia - Frontiers in immunology, 2017 - frontiersin.org
Bullous pemphigoid (BP) is by far the most common autoimmune blistering dermatosis that
mainly occurs in the elderly. The BP180 is a transmembrane glycoprotein, which is highly …

[HTML][HTML] The therapeutic strategies for SLE by targeting anti-dsDNA antibodies

Y Wang, S Xiao, Y Xia, H Wang - Clinical reviews in allergy & immunology, 2022 - Springer
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by
diverse serological autoantibodies. Anti-dsDNA antibodies are involved in multiple organ …

[HTML][HTML] Regulation of Fn14 receptor and NF-κB underlies inflammation in Meniere's disease

L Frejo, T Requena, S Okawa… - Frontiers in …, 2017 - frontiersin.org
Meniere's disease (MD) is a rare disorder characterized by episodic vertigo, sensorineural
hearing loss, tinnitus, and aural fullness. It is associated with a fluid imbalance between the …

[HTML][HTML] An overview of neonatal lupus with anti-Ro characteristics

M Gryka-Marton, D Szukiewicz… - International Journal of …, 2021 - mdpi.com
Neonatal lupus erythematosus (NLE) is a syndrome of clinical symptoms observed in
neonates born to mothers with antibodies to soluble antigens of the cell nucleus. The main …

TWEAK/Fn14 activation participates in skin inflammation

Q Liu, S Xiao, Y Xia - Mediators of Inflammation, 2017 - Wiley Online Library
Tumor necrosis factor‐(TNF‐) like weak inducer of apoptosis (TWEAK) participates in
multiple biological activities via binding to its sole receptor—fibroblast growth factor …