Physical activity, by definition, is any skeletal muscle body movement that results in energy
expenditure. In the last few decades, a plethora of scientific evidences have accumulated …

Disease-modifying drugs have mostly failed as treatments for progressive multiple sclerosis.
Management of the disease therefore solely aims to minimise symptoms and, if possible …

Multiple sclerosis (MS) is a chronic autoimmune inflammatory disease of the central nervous
system, leading to neurodegeneration and manifesting as a variety of symptoms. These can …

The prevalence, associations, and natural history of pain in multiple sclerosis (MS) are
poorly understood. The objective of this work was to study the prevalence of pain syndromes …

Detecting clinically significant symptoms of depression and anxiety in medically ill patients
using self-report rating scales presents a challenge because of somatic confounders. The …

Physical activity has been associated with a small improvement in quality of life (QOL)
among those with multiple sclerosis (MS). This relationship may be indirect and operate …

A number of high-quality studies have recently been published that examine the association
between neuropathic pain and health-related quality of life (HRQoL). The current review …

Pain is common in patients with multiple sclerosis (MS), but estimates of its prevalence have
varied widely. The literature describing pain in MS patients spans four decades and has …

Chronic pain is common in patients with neurologic complications of a central nervous
system insult such as stroke. The pain is most commonly musculoskeletal or related to …

Cognitive impairment has been reported at all phases and all subtypes of multiple sclerosis.
It remains a major cause of neurological disability in young and middle-aged adults suffering …