The development of microelectrode arrays (MEAs) along with complementary advances in
electronics, mechanics and software to connect with these arrays has led to the in vitro …

Exocytosis is one of the essential steps for chemical signal transmission between neurons.
In this process, vesicles dock and fuse with the plasma membrane and release the stored …

For decades, carbon-fiber microelectrodes have been used in amperometric measurements
of neurotransmitter release at a wide variety of cell types, providing a tremendous amount of …

A potentiostat circuit for the application of bipolar electrode voltages and detection of
bidirectional currents using a microelectrode array is presented. The potentiostat operates …

Human neuroblastoma cells, SH-SY5Y, are often used as a neuronal model to study
Parkinson's disease and dopamine release in the substantia nigra, a midbrain region that …

Vesicular exocytosis is a ubiquitous bio-process involved in plenty of normal and pathologic
events in living cells and has received increasing research attention. After decades of …

Volcano-shaped microelectrodes have demonstrated superior performance in measuring
attenuated intracellular action potentials from cardiomyocyte cultures. However, their …

Featured Application Animal testing will be soon replaced by better accepted and less
expensive in-vitro cell culture models, which explains the recent demand for real-time cell …

Large-scale microelectrode arrays offers enhanced spatiotemporal resolution in
electrophysiology studies. In this paper, we discuss the design and performance of an …

Amperometry is arguably the most widely used technique for studying the exocytosis of
biological amines. However, the scarcity of human tissues, particularly in the context of …