The day of extubation is a critical time during an intensive care unit (ICU) stay. Extubation is
usually decided after a weaning readiness test involving spontaneous breathing on a T …

Background Extubation failure is an important issue in ventilated patients and its risk factors
remain a matter of research. We conducted a systematic review and meta-analysis to …

Background: Interventions that lead to earlier liberation from mechanical ventilation can
improve patient outcomes. This guideline, a collaborative effort between the American …

Importance High-flow nasal oxygen may prevent postextubation respiratory failure in the
intensive care unit (ICU). The combination of high-flow nasal oxygen with noninvasive …

Objective: The influence of delirium, ICU-acquired paresis, and cardiac performance on
extubation outcome has never been evaluated together. We aimed to assess the respective …

Purpose Systematic review and network meta-analysis to investigate the efficacy of
noninvasive respiratory strategies, including noninvasive positive pressure ventilation …

Current research is focusing on preventing extubation failure, especially in the most
challenging cases. The use of weaning protocols–written or computerized–attempts to early …

Background: Extubation failure (EF) can lead to an increased chance of ventilator-
associated pneumonia, longer hospital stays, and a higher mortality rate. This study aimed …

Introduction Contemporary information on mechanical ventilation (MV) use in emerging
countries is limited. Moreover, most epidemiological studies on ventilatory support were …

Background Weaning from mechanical ventilation is a challenging step during recovery from
critical illness. Weaning failure or early reintubation are associated with increased morbidity …