Revisiting the continuum model of tendon pathology: what is its merit in clinical practice and research?

JL Cook, E Rio, CR Purdam, SI Docking - British journal of sports …, 2016 - bjsm.bmj.com
The pathogenesis of tendinopathy and the primary biological change in the tendon that
precipitates pathology have generated several pathoaetiological models in the literature …

Is tendon pathology a continuum? A pathology model to explain the clinical presentation of load-induced tendinopathy

JL Cook, CR Purdam - British journal of sports medicine, 2009 - bjsm.bmj.com
Overuse tendinopathy is problematic to manage clinically. People of different ages with
tendons under diverse loads present with varying degrees of pain, irritability, and capacity to …

Organoids for drug discovery and personalized medicine

T Takahashi - Annual review of pharmacology and toxicology, 2019 - annualreviews.org
A wide variety of organs are in a dynamic state, continuously undergoing renewal as a result
of constant growth and differentiation. Stem cells are required during these dynamic events …

The pain of tendinopathy: physiological or pathophysiological?

E Rio, L Moseley, C Purdam, T Samiric, D Kidgell… - Sports medicine, 2014 - Springer
Tendon pain remains an enigma. Many clinical features are consistent with tissue disruption—
the pain is localised, persistent and specifically associated with tendon loading, whereas …

Tendinopathy: injury, repair, and current exploration

K Lipman, C Wang, K Ting, C Soo… - … design, development and …, 2018 - Taylor & Francis
Both acute and chronic tendinopathy result in high morbidity, requiring management that is
often lengthy and expensive. However, limited and conflicting scientific evidence …

Chronic tendinopathy tissue pathology, pain mechanisms, and etiology with a special focus on inflammation

U Fredberg… - Scandinavian journal of …, 2008 - Wiley Online Library
Continuing progress in research in molecular biology and biomechanics has provided
considerable new information and has given rise to new hypotheses in chronic …

Sports and exercise-related tendinopathies: a review of selected topical issues by participants of the second International Scientific Tendinopathy Symposium (ISTS) …

A Scott, S Docking, B Vicenzino, H Alfredson… - British journal of sports …, 2013 - bjsm.bmj.com
In September 2010, the first International Scientific Tendinopathy Symposium (ISTS) was
held in Umeå, Sweden, to establish a forum for original scientific and clinical insights in this …

Basic aspects of musculoskeletal pain: from acute to chronic pain

L Arendt-Nielsen… - Journal of Manual & …, 2011 - Taylor & Francis
The transition from acute to chronic musculoskeletal pain is not well understood. To
understand this transition, it is important to know how peripheral and central sensitization …

Novel approaches for the management of tendinopathy

N Maffulli, UG Longo, V Denaro - JBJS, 2010 - journals.lww.com
➤ Eccentric exercises have been proposed to promote collagen fiber cross-link formation
within the tendon, thereby facilitating tendon remodeling. Overall results suggest a trend for …

The challenge of managing tendinopathy in competing athletes

JL Cook, CR Purdam - British journal of sports medicine, 2014 - bjsm.bmj.com
Managing tendinopathy in season is a challenge for all sports medicine practitioners. Many
of the strategies employed to treat tendinopathy in a rehabilitation setting are not suitable …