Revisiting the continuum model of tendon pathology: what is its merit in clinical practice and research?
The pathogenesis of tendinopathy and the primary biological change in the tendon that
precipitates pathology have generated several pathoaetiological models in the literature …
precipitates pathology have generated several pathoaetiological models in the literature …
Is tendon pathology a continuum? A pathology model to explain the clinical presentation of load-induced tendinopathy
JL Cook, CR Purdam - British journal of sports medicine, 2009 - bjsm.bmj.com
Overuse tendinopathy is problematic to manage clinically. People of different ages with
tendons under diverse loads present with varying degrees of pain, irritability, and capacity to …
tendons under diverse loads present with varying degrees of pain, irritability, and capacity to …
Organoids for drug discovery and personalized medicine
T Takahashi - Annual review of pharmacology and toxicology, 2019 - annualreviews.org
A wide variety of organs are in a dynamic state, continuously undergoing renewal as a result
of constant growth and differentiation. Stem cells are required during these dynamic events …
of constant growth and differentiation. Stem cells are required during these dynamic events …
The pain of tendinopathy: physiological or pathophysiological?
Tendon pain remains an enigma. Many clinical features are consistent with tissue disruption—
the pain is localised, persistent and specifically associated with tendon loading, whereas …
the pain is localised, persistent and specifically associated with tendon loading, whereas …
Tendinopathy: injury, repair, and current exploration
Both acute and chronic tendinopathy result in high morbidity, requiring management that is
often lengthy and expensive. However, limited and conflicting scientific evidence …
often lengthy and expensive. However, limited and conflicting scientific evidence …
Chronic tendinopathy tissue pathology, pain mechanisms, and etiology with a special focus on inflammation
U Fredberg… - Scandinavian journal of …, 2008 - Wiley Online Library
Continuing progress in research in molecular biology and biomechanics has provided
considerable new information and has given rise to new hypotheses in chronic …
considerable new information and has given rise to new hypotheses in chronic …
Sports and exercise-related tendinopathies: a review of selected topical issues by participants of the second International Scientific Tendinopathy Symposium (ISTS) …
In September 2010, the first International Scientific Tendinopathy Symposium (ISTS) was
held in Umeå, Sweden, to establish a forum for original scientific and clinical insights in this …
held in Umeå, Sweden, to establish a forum for original scientific and clinical insights in this …
Basic aspects of musculoskeletal pain: from acute to chronic pain
L Arendt-Nielsen… - Journal of Manual & …, 2011 - Taylor & Francis
The transition from acute to chronic musculoskeletal pain is not well understood. To
understand this transition, it is important to know how peripheral and central sensitization …
understand this transition, it is important to know how peripheral and central sensitization …
Novel approaches for the management of tendinopathy
N Maffulli, UG Longo, V Denaro - JBJS, 2010 - journals.lww.com
➤ Eccentric exercises have been proposed to promote collagen fiber cross-link formation
within the tendon, thereby facilitating tendon remodeling. Overall results suggest a trend for …
within the tendon, thereby facilitating tendon remodeling. Overall results suggest a trend for …
The challenge of managing tendinopathy in competing athletes
JL Cook, CR Purdam - British journal of sports medicine, 2014 - bjsm.bmj.com
Managing tendinopathy in season is a challenge for all sports medicine practitioners. Many
of the strategies employed to treat tendinopathy in a rehabilitation setting are not suitable …
of the strategies employed to treat tendinopathy in a rehabilitation setting are not suitable …