The intestinal microbiome in early life: health and disease

MC Arrieta, LT Stiemsma, N Amenyogbe… - Frontiers in …, 2014 - frontiersin.org
Human microbial colonization begins at birth and continues to develop and modulate in
species abundance for about 3 years, until the microbiota becomes adult-like. During the …

Strategies for culture of 'unculturable'bacteria

SR Vartoukian, RM Palmer… - FEMS microbiology …, 2010 - academic.oup.com
Molecular ecology methods are now well established for the culture-independent
characterization of complex bacterial communities associated with various environmental …

Phylogenetically novel uncultured microbial cells dominate earth microbiomes

KG Lloyd, AD Steen, J Ladau, J Yin, L Crosby - MSystems, 2018 - Am Soc Microbiol
To describe a microbe's physiology, including its metabolism, environmental roles, and
growth characteristics, it must be grown in a laboratory culture. Unfortunately, many …

Cultivation of unculturable soil bacteria

VHT Pham, J Kim - Trends in biotechnology, 2012 - cell.com
Despite the abundance of bacterial species in soil, more than 99% of these species cannot
be cultured by traditional techniques. In addition, the less than 1% of bacteria that can be …

Bacterial unculturability and the formation of intercellular metabolic networks

S Pande, C Kost - Trends in microbiology, 2017 - cell.com
The majority of known bacterial species cannot be cultivated under laboratory conditions.
Here we argue that the adaptive emergence of obligate metabolic interactions in natural …

[HTML][HTML] A review of prokaryotic populations and processes in sub-seafloor sediments, including biosphere: geosphere interactions

RJ Parkes, B Cragg, E Roussel, G Webster… - Marine Geology, 2014 - Elsevier
A general review of the sub-seafloor biosphere is presented. This includes an update and
assessment of prokaryotic cell distributions within marine sediments, current deepest 1922 …

Biogeographical distribution and diversity of microbes in methane hydrate-bearing deep marine sediments on the Pacific Ocean Margin

F Inagaki, T Nunoura, S Nakagawa… - Proceedings of the …, 2006 - National Acad Sciences
The deep subseafloor biosphere is among the least-understood habitats on Earth, even
though the huge microbial biomass therein plays an important role for potential long-term …

A guide to successful bioprospecting: informed by actinobacterial systematics

M Goodfellow, HP Fiedler - Antonie Van Leeuwenhoek, 2010 - Springer
New structurally diverse natural products are discovered when novel screening procedures
are introduced or when high quality biological materials from new sources are examined in …

Culture-dependent and-independent methods capture different microbial community fractions in hydrocarbon-contaminated soils

FOP Stefani, TH Bell, C Marchand… - PloS one, 2015 - journals.plos.org
Bioremediation is a cost-effective and sustainable approach for treating polluted soils, but
our ability to improve on current bioremediation strategies depends on our ability to isolate …

Cultivating the uncultured: limits, advances and future challenges

K Alain, J Querellou - Extremophiles, 2009 - Springer
Since the invention of the Petri dish, there have been continuous efforts to improve efficiency
in microbial cultivation. These efforts were devoted to the attainment for diverse growth …