Aptamer-based biosensors and nanosensors for the detection of vascular endothelial growth factor (VEGF): A review

S Dehghani, R Nosrati, M Yousefi, A Nezami… - Biosensors and …, 2018 - Elsevier
Vascular endothelial growth factor (VEGF) is a key regulator of vascular formation and a
predominant protein biomarker in cancer angiogenesis. Owing to its crucial roles in the …

Anti‐VEGF DNA‐based aptamers in cancer therapeutics and diagnostics

C Riccardi, E Napolitano, C Platella… - Medicinal Research …, 2021 - Wiley Online Library
The vascular endothelial growth factor (VEGF) family and its receptors play fundamental
roles not only in physiological but also in pathological angiogenesis, characteristic of cancer …

Development of a molecularly imprinted polymer tailored on disposable screen-printed electrodes for dual detection of EGFR and VEGF using nano-liposomal …

M Johari-Ahar, P Karami, M Ghanei, A Afkhami… - Biosensors and …, 2018 - Elsevier
This work demonstrates the development of a gold screen-printed electrode (Au-SPE)-
based biosensor modified with a molecularly imprinted polymer and amplified using …

Recent advances in aptamer-based sensors for breast cancer diagnosis: special cases for nanomaterial-based VEGF, HER2, and MUC1 aptasensors

S Şahin, MO Caglayan, Z Üstündağ - Microchimica Acta, 2020 - Springer
Cancer is one of the most common and important diseases with a high mortality rate. Breast
cancer is among the three most common types of cancer in women, and the mortality rate …

Affinity Improvement of a VEGF Aptamer by in Silico Maturation for a Sensitive VEGF-Detection System

Y Nonaka, W Yoshida, K Abe, S Ferri… - Analytical …, 2013 - ACS Publications
Systematic evolution of ligands by exponential enrichment (SELEX) is an efficient method to
identify aptamers; however, it sometimes fails to identify aptamers that bind to their target …

Electrochemical biosensors combining aptamers and enzymatic activity: Challenges and analytical opportunities

A Rhouati, JL Marty, A Vasilescu - Electrochimica Acta, 2021 - Elsevier
The combination between the specific recognition abilities of aptamers and the catalytic
power of enzymes represents a powerful tool in bioanalysis to achieve the highly selective …

[HTML][HTML] Screening and biosensor-based approaches for lung cancer detection

L Wang - Sensors, 2017 - mdpi.com
Early diagnosis of lung cancer helps to reduce the cancer death rate significantly. Over the
years, investigators worldwide have extensively investigated many screening modalities for …

Aptamer-based LoC-SERS sensing system for rapid and highly sensitive detection of gastric cancer

M Chen, S Yao, Y Yang, F Jiang, Y Yang, Y Gu… - Microchemical …, 2023 - Elsevier
Multiplex detection of biomarkers is nontrivial for gastric cancer diagnosis. Herein, we
presented a lab-on-a-chip surface-enhanced Raman scattering (LoC-SERS) sensing system …

A signal-on nanobiosensor for VEGF165 detection based on supraparticle copper nanoclusters formed on bivalent aptamer

FM Moghadam, M Rahaie - Biosensors and Bioelectronics, 2019 - Elsevier
In this study, a signal-on nanobiosensor based on bivalent aptamer-Cu nanocluster was
designed and optimized for specific and sensitive detection of VEGF 165. The VEGF 165 is …

[HTML][HTML] Early lung cancer diagnosis by biosensors

Y Zhang, D Yang, L Weng, L Wang - International journal of molecular …, 2013 - mdpi.com
Lung cancer causes an extreme threat to human health, and the mortality rate due to lung
cancer has not decreased during the last decade. Prognosis or early diagnosis could help …