Bone grafts have been predominated used to treat bone defects, delayed union or non-
union, and spinal fusion in orthopaedic clinically for a period of time, despite the emergency …

Zinc is a micronutrient of key importance for human health. An increasing number of studies
indicate that zinc plays a significant role in bone tissue's normal development and …

Highlights•Alternative bone regenerative therapeutics are needed.•Ions have been
proposed to regenerate skeletal tissue.•Drug delivery systems have been studied to deliver …

Zinc is an essential mineral that is required for normal skeletal growth and bone
homeostasis. Furthermore, zinc appears to be able to promote bone regeneration. However …

Additive manufacturing has received attention for the fabrication of medical implants that
have customized and complicated structures. Biodegradable Zn metals are revolutionary …

Several inorganic materials such as special compositions of silicate glasses, glass-ceramics
and calcium phosphates have been shown to be bioactive and resorbable and to exhibit …

Bioactive glass and glass–ceramics are used in bone repair applications and are being
developed for tissue engineering applications. Bioactive glasses/Bioglass are very attractive …

Over the last 4 decades innovations in biomaterials and medical technology have had a
sustainable impact on the development of biopolymers, titanium/stainless steel and …

Owing to the insufficient guidance of new bone formation in orthopedic and
craniomaxillofacial surgery, construction of a guided bone regeneration membrane to …

This article provides an overview on the application of metallic ions in the fields of
regenerative medicine and tissue engineering, focusing on their therapeutic applications …