Thyroid hormones are crucial for organismal development and homeostasis. In humans,
untreated congenital hypothyroidism due to thyroid agenesis inevitably leads to cretinism …

The gastrointestinal tract develops from a simple and uniform tube into a complex organ with
specific differentiation patterns along the anterior–posterior and dorso-ventral axes of …

Abstract Cytidine (C) to Uridine (U) RNA editing is a post‐transcriptional modification that is
accomplished by the deaminase APOBEC 1 and its partnership with the RNA‐binding …

The mechanisms by which the tumor behaviors of hepatocellular carcinoma (HCC) support
growth and metastasis remain largely unknown, and it has become increasingly apparent …

Separation of the single anterior foregut tube into the esophagus and trachea involves cell
proliferation and differentiation, as well as dynamic changes in cell–cell adhesion and …

RNA-binding proteins (RBPs) are critical players in the post-transcriptional regulation of
gene expression and are associated with each event in RNA metabolism. The term 'RNA …

Abstract RNA-binding protein 47 (RBM47) is required for embryonic endoderm
development, but a role in adult intestine is unknown. We studied intestine-specific Rbm47 …

Mammalian C to U RNA is mediated by APOBEC1, the catalytic deaminase, together with
RNA binding cofactors (including A1CF and RBM47) whose relative physiological …

Rho GTPases play central roles in a wide variety of cellular processes, including
cytoskeletal dynamics, cell adhesion and cell polarity. RhoU and RhoV are Rho GTPases …

Abstract Background Anaplastic Thyroid Cancer (ATC) is an undifferentiated and aggressive
tumor that often originates from well-Differentiated Thyroid Carcinoma (DTC) through a trans …