Epigenetic clocks and female fertility timeline: A new approach to an old issue?
L Li Piani, P Vigano', E Somigliana - Frontiers in cell and …, 2023 - frontiersin.org
Worldwide increase in life expectancy has boosted research on aging. Overcoming the
concept of chronological age, higher attention has been addressed to biological age, which …
concept of chronological age, higher attention has been addressed to biological age, which …
The effect of low birth weight as an intrauterine exposure on the early onset of sarcopenia through possible molecular pathways
D Celik, M Campisi, L Cannella… - Journal of Cachexia …, 2024 - Wiley Online Library
Sarcopenia, a musculoskeletal disease characterized by the progressive loss of skeletal
muscle mass, strength, and physical performance, presents significant challenges to global …
muscle mass, strength, and physical performance, presents significant challenges to global …
Blood-based epigenome-wide analyses of cognitive abilities
Background Blood-based markers of cognitive functioning might provide an accessible way
to track neurodegeneration years prior to clinical manifestation of cognitive impairment and …
to track neurodegeneration years prior to clinical manifestation of cognitive impairment and …
Birth weight and maternal energy status during pregnancy as predictors of epigenetic age acceleration in young adults from metropolitan Cebu, Philippines
Epigenetic clocks quantify regular changes in DNA methylation that occur with age, or in
relation to biomarkers of ageing, and are strong predictors of morbidity and mortality. Here …
relation to biomarkers of ageing, and are strong predictors of morbidity and mortality. Here …
Creating and validating a DNA methylation-based proxy for interleukin-6
Background Studies evaluating the relationship between chronic inflammation and cognitive
functioning have produced heterogeneous results. A potential reason for this is the …
functioning have produced heterogeneous results. A potential reason for this is the …
Identification of epigenome-wide DNA methylation differences between carriers of APOE ε4 and APOE ε2 alleles
Abstract Background The apolipoprotein E (APOE) ε4 allele is the strongest genetic risk
factor for late onset Alzheimer's disease, whilst the ε2 allele confers protection. Previous …
factor for late onset Alzheimer's disease, whilst the ε2 allele confers protection. Previous …
Low birthweight is associated with epigenetic age acceleration in the first 3 years of life
Abstract Background and objectives The Developmental Origins of Health and Disease
hypothesis posits that early life adversity is associated with poor adult health outcomes …
hypothesis posits that early life adversity is associated with poor adult health outcomes …
Methylome-wide association study of early life stressors and adult mental health
The environment and events that we are exposed to in utero, during birth and in early
childhood influence our future physical and mental health. The underlying mechanisms that …
childhood influence our future physical and mental health. The underlying mechanisms that …
Epigenetic signature of very low birth weight in young adult life
Background Globally, one in ten babies is born preterm (< 37 weeks), and 1–2% preterm at
very low birth weight (VLBW,< 1500 g). As adults, they are at increased risk for a plethora of …
very low birth weight (VLBW,< 1500 g). As adults, they are at increased risk for a plethora of …
Birth size and the serum level of biological age markers in men
A Żelaźniewicz, J Nowak-Kornicka, B Pawłowski - Scientific Reports, 2023 - nature.com
Previous studies showed that intrauterine growth restrictions, resulting in smaller body size
at birth, are associated with altered development and the risk of age-related diseases in …
at birth, are associated with altered development and the risk of age-related diseases in …