Arrhythmogenic cardiomyopathy is a genetic disorder characterized by the risk of life-
threatening arrhythmias, myocardial dysfunction and fibrofatty replacement of myocardial …

Arrhythmogenic right ventricular cardiomyopathy is a rare inherited heart-muscle disease
that is a cause of sudden death in young people and athletes. Causative mutations in genes …

Background Loss of myocytes is an important mechanism in the development of cardiac
failure of either ischemic or nonischemic origin. However, whether programmed cell death …

Objectives. The aim of the present investigation was to redefine the clinicopathologic profile
of arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC), with special reference …

Arrhythmogenic cardiomyopathy (ACM) is a primary disease of the myocardium,
predominantly caused by genetic defects in proteins of the cardiac intercalated disc …

Apoptosis is a highly regulated process of cell deletion and plays a fundamental role in the
maintenance of tissue homeostasis in the adult organism. Numerous studies in recent years …

Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVC) is a genetic disease
caused by mutations in desmosomal proteins. The phenotypic hallmark of ARVC is …

Arrhythmogenic right ventricular dysplasia type 2 (ARVD2, OMIM 600996) is an autosomal
dominant cardiomyopathy, characterized by partial degeneration of the myocardium of the …

The 364 exon TTN gene encodes titin (TTN), the largest known protein, which plays key
structural, developmental, mechanical, and regulatory roles in cardiac and skeletal muscles …

Since Kerr et al1 in 1972 coined the term “apoptosis” for a morphologically distinct mode of
cell death, this concept of cell suicide has gained increasing interest in cytology and …