Fluidic systems with nanometre length scales enable sensitive analysis of DNA molecules.
Nanofluidic systems have been used to probe conformational, dynamic, and entropic …

Single molecule force spectroscopy is a powerful method that uses the mechanical
properties of DNA to explore DNA interactions. Here we describe how DNA stretching …

DNA intercalators are widely used as fluorescent probes to visualize DNA and DNA
transactions in vivo and in vitro. It is well known that they perturb DNA structure and stability …

YOYO-1 is a fluorescent dye widely used for probing the statistical–mechanical properties of
DNA. However, currently contradicting data exist how YOYO-1 binding alters the DNA …

SYBR Gold is a commonly used and particularly bright fluorescent DNA stain, however, its
chemical structure is unknown and its binding mode to DNA remains controversial. Here, we …

Picking up at the conclusion of Viovy's review of the physics of gel electrophoresis [J.-L.
Viovy, Rev. Mod. Phys. 72, 813 (2000) 10.1103/RevModPhys. 72.813], this review …

We have used the interface between a nanochannel and a microchannel as a tool for
applying controlled forces on a DNA molecule. A molecule, with a radius of gyration larger …

The details surrounding the crossover from wormlike-specific to universal polymeric
behavior has been the subject of debate and confusion even for the simple case of a dilute …

Fully stretched DNA molecules are becoming a fundamental component of new systems for
comprehensive genome analysis. Among a number of approaches for elongating DNA …

There is a wide range of applications for non-covalent DNA binding ligands, and
optimization of such interactions requires detailed understanding of the binding …