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Observational cohorts have emerged as important resources to study course and prognosis
of chronic disease, and also facilitate phenotype definition for genetic studies. We describe …

Stevens–Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are severe,
cutaneous adverse drug reactions that are rare but life threatening. Genetic biomarkers for …

Psoriasis vulgaris and psoriatic arthritis (PsA) are inter-related heritable diseases. Psoriatic
skin is characterized by hyperproliferative, poorly differentiated keratinocytes and severe …

Rheumatoid arthritis (RA) is a systemic autoimmune disease resulting in chronic
inflammation of the synovium and consequent cartilage and bone erosion. RA is associated …

Behcet's disease (BD) is a chronic refractory multi-system autoimmune disorder that occurs
in a genetically susceptible host. Multiple genetic factors have been identified that may …

Systemic sclerosis (SSc) is a severe connective tissue disorder characterized by extensive
fibrosis, vascular damage, and autoimmune events. During the last years, the number of …

In this paper, we aim at discovering genetic factors of psoriasis through searching for
statistically significant SNP-SNP interactions exhaustively from two real psoriasis genome …

Severe cutaneous adverse drug reactions (SCARs) are life‐threatening reactions. The
strong association between the HLA-B∗ 58: 01 allele and allopurinol‐induced SCARs is …

Abstract PSORS1C1/CDSN is a susceptibility gene for psoriasis. Both psoriasis and
rheumatoid arthritis (RA) are autoimmune diseases. This study investigated whether …