[HTML][HTML] Nano-enhanced drug delivery and therapeutic ultrasound for cancer treatment and beyond
P Tharkar, R Varanasi, WSF Wong, CT Jin… - … in Bioengineering and …, 2019 - frontiersin.org
While ultrasound is most widely known for its use in diagnostic imaging, the energy carried
by ultrasound waves can be utilized to influence cell function and drug delivery …
by ultrasound waves can be utilized to influence cell function and drug delivery …
Nucleation, mapping and control of cavitation for drug delivery
E Stride, C Coussios - Nature Reviews Physics, 2019 - nature.com
Acoustically driven bubbles produce a range of mechanical, thermal and chemical effects
that can be exploited in drug delivery applications. Significant improvements in the targeting …
that can be exploited in drug delivery applications. Significant improvements in the targeting …
Applications of ultrasound-mediated drug delivery and gene therapy
Gene therapy has continuously evolved throughout the years since its first proposal to
develop more specific and effective transfection, capable of treating a myriad of health …
develop more specific and effective transfection, capable of treating a myriad of health …
Sonoporation: Past, present, and future
A surge of research in intracellular delivery technologies is underway with the increased
innovations in cell‐based therapies and cell reprogramming. Particularly, physical cell …
innovations in cell‐based therapies and cell reprogramming. Particularly, physical cell …
[HTML][HTML] Opening of endothelial cell–cell contacts due to sonoporation
Ultrasound insonification of microbubbles can locally increase vascular permeability to
enhance drug delivery. To control and optimize the therapeutic potential, we need to better …
enhance drug delivery. To control and optimize the therapeutic potential, we need to better …
Buckling of lipidic ultrasound contrast agents under quasi-static load
G Chabouh, B van Elburg… - … of the Royal …, 2023 - royalsocietypublishing.org
Collapse of lipidic ultrasound contrast agents under high-frequency compressive load has
been historically interpreted by the vanishing of surface tension. By contrast, buckling of …
been historically interpreted by the vanishing of surface tension. By contrast, buckling of …
Ultrasound contrast: gas microbubbles in the vasculature
AL Klibanov - Investigative Radiology, 2021 - journals.lww.com
Gas-filled microbubbles are currently in clinical use as blood pool contrast agents for
ultrasound imaging. The goal of this review is to discuss the trends and issues related to …
ultrasound imaging. The goal of this review is to discuss the trends and issues related to …
Polymeric materials for ultrasound imaging and therapy
Ultrasound (US) is routinely used for diagnostic imaging and increasingly employed for
therapeutic applications. Materials that act as cavitation nuclei can improve the resolution of …
therapeutic applications. Materials that act as cavitation nuclei can improve the resolution of …
An overview of cell membrane perforation and resealing mechanisms for localized drug delivery
Localized and reversible plasma membrane disruption is a promising technique employed
for the targeted deposition of exogenous therapeutic compounds for the treatment of …
for the targeted deposition of exogenous therapeutic compounds for the treatment of …
A multicellular brain spheroid model for studying the mechanisms and bioeffects of ultrasound-enhanced drug penetration beyond the blood‒brain barrier
AN Paranjape, L D'Aiuto, W Zheng, X Chen… - Scientific Reports, 2024 - nature.com
The blood‒brain barrier (BBB) acts as a hindrance to drug therapy reaching the brain. With
an increasing incidence of neurovascular diseases and brain cancer metastases, there is a …
an increasing incidence of neurovascular diseases and brain cancer metastases, there is a …