Esrra regulates Rplp1-mediated translation of lysosome proteins suppressed in metabolic dysfunction-associated steatohepatitis and reversed by alternate day fasting

M Tripathi, K Gauthier, R Sandireddy, J Zhou… - Molecular …, 2024 - Elsevier
Objective Currently, little is known about the mechanism (s) regulating global and specific
protein translation during metabolic dysfunction-associated steatohepatitis (MASH; …

Sweet science: Exploring the impact of fructose and glucose on brown adipocyte differentiation using optical diffraction tomography

P Anantha, X Wu, S Elsaid, P Raj, I Barman, SS Tee - bioRxiv, 2024 - biorxiv.org
The thermogenic capacity of brown adipose tissue (BAT) has garnered much attention for its
potential to regulate systemic energy balance. BAT depot size and function need to be tightly …

Esrra regulates Rplp1-mediated translation of lysosome proteins suppressed in non-alcoholic steatohepatitis and reversed by alternate day fasting

M Tripathi, K Gauthier, R Sandireddy, J Zhou, P Gupta… - bioRxiv, 2021 - biorxiv.org
Although general translation declines during fasting, maintaining the translation of a subset
or proteins is necessary for metabolic homeostasis and cell viability. Using unbiased …