Biosensor-based microRNA detection: techniques, design, performance, and challenges

BN Johnson, R Mutharasan - Analyst, 2014 - pubs.rsc.org
The current state of biosensor-based techniques for amplification-free microRNA (miRNA)
detection is critically reviewed. Comparison with non-sensor and amplification-based …

[HTML][HTML] Metagenomic investigation of gastrointestinal microbiome in cattle

M Kim, T Park, Z Yu - Asian-Australasian journal of animal sciences, 2017 - ncbi.nlm.nih.gov
The gastrointestinal (GI) tract, including the rumen and the other intestinal segments of
cattle, harbors a diverse, complex, and dynamic microbiome that drives feed digestion and …

Transcriptome analysis of parallel-evolved Escherichia coli strains under ethanol stress

T Horinouchi, K Tamaoka, C Furusawa, N Ono… - BMC genomics, 2010 - Springer
Background Understanding ethanol tolerance in microorganisms is important for the
improvement of bioethanol production. Hence, we performed parallel-evolution experiments …

Development of a single tube 640-plex genotyping method for detection of nucleic acid variations on microarrays

K Krjutškov, R Andreson, R Mägi… - Nucleic acids …, 2008 - academic.oup.com
Detection of DNA sequence variation is critical to biomedical applications, including disease
genetic identification, diagnosis and treatment, drug discovery and forensic analysis. Here …

Transition from positive to neutral in mutation fixation along with continuing rising fitness in thermal adaptive evolution

T Kishimoto, L Iijima, M Tatsumi, N Ono, A Oyake… - PLoS …, 2010 - journals.plos.org
It remains to be determined experimentally whether increasing fitness is related to positive
selection, while stationary fitness is related to neutral evolution. Long-term laboratory …

[HTML][HTML] Detection of breast cancer-related point-mutations using screen-printed and gold-plated electrochemical sensor arrays suitable for point-of-care applications

V Thöny, E Melnik, M Asadi, P Mehrabi… - Talanta Open, 2022 - Elsevier
For anticancer therapy and disease prognosis in breast cancer, three PIK3CA point-
mutations (H1047R, E545K, and E542K) play a significant role. To allow for specific and …

Whole mitochondrial genome capture from faecal samples and museum‐preserved specimens

T Van der Valk, F Lona Durazo, L Dalén… - Molecular ecology …, 2017 - Wiley Online Library
Population‐scale molecular studies of endangered and cryptic species are often limited by
access to high‐quality samples. The use of noninvasively collected samples or museum …

Electrostatic melting in a single-molecule field-effect transistor with applications in genomic identification

S Vernick, SM Trocchia, SB Warren, EF Young… - Nature …, 2017 - nature.com
The study of biomolecular interactions at the single-molecule level holds great potential for
both basic science and biotechnology applications. Single-molecule studies often rely on …

Inference of transcriptome signatures of Escherichia coli in long-term stationary phase

S Takano, H Takahashi, Y Yama, R Miyazaki… - Scientific Reports, 2023 - nature.com
Abstract “Non-growing” is a dominant life form of microorganisms in nature, where available
nutrients and resources are limited. In laboratory culture systems, Escherichia coli can …

Sexual dimorphism and aging in the human hyppocampus: identification, validation, and impact of differentially expressed genes by factorial microarray and network …

DV Guebel, NV Torres - Frontiers in aging neuroscience, 2016 - frontiersin.org
Motivation: In the brain of elderly-healthy individuals, the effects of sexual dimorphism and
those due to normal aging appear overlapped. Discrimination of these two dimensions …