Leptospirosis is a widespread zoonosis caused by pathogenic Leptospira spp. It is
considered a neglected infectious disease of human and veterinary concern. Our group has …

The mechanisms of disease pathogenesis in leptospirosis are poorly defined. Recent
developments in the application of genetic tools in the study of Leptospira have advanced …

Pathogenic spirochaetes of the genus Leptospira are the etiological agents of leptospirosis,
a zoonotic infection worldwide. The disease is considered an emerging and re-emerging …

Both coagulation and fibrinolysis are tightly connected with the innate immune system.
Infection and inflammation cause profound alterations in the otherwise well-controlled …

Acinetobacter baumannii is an emerging opportunistic pathogen, responsible for up to 10%
of gram-negative, nosocomial infections. The global increase of multidrug-resistant and pan …

The plasminogen (Plg) system plays an important homeostatic role in the degradation of
fibrin clots, extracellular matrices and tissue barriers important for cellular migration, as well …

Leptospirosis is the most emerging zoonotic disease of epidemic potential caused by
pathogenic species of Leptospira. The bacterium invades the host system and causes the …

The pathogenic spirochetes Borrelia burgdorferi, B. hermsii, B. recurrentis, Treponema
denticola and Leptospira spp. are the etiologic agents of Lyme disease, relapsing fever …

Vascular inflammation is a complex and multifactorial pathophysiological process that plays
a crucial role in all stages of syphilis and is responsible for tissue damage. Little is known …

The recombinant Treponema pallidum protein Tp0965 (rTp0965), one of the many proteins
derived from the genome of T. pallidum subsp. pallidum, shows strong immunogenicity and …