Imaging biomarkers for evaluating tumor response: RECIST and beyond

CC Ko, LR Yeh, YT Kuo, JH Chen - Biomarker research, 2021 - Springer
Abstract Response Evaluation Criteria in Solid Tumors (RECIST) is the gold standard for
assessment of treatment response in solid tumors. Morphologic change of tumor size …

Twenty years on: RECIST as a biomarker of response in solid tumours an EORTC imaging group–ESOI joint paper

L Fournier, LF de Geus-Oei, D Regge… - Frontiers in …, 2022 - frontiersin.org
Response evaluation criteria in solid tumours (RECIST) v1. 1 are currently the reference
standard for evaluating efficacy of therapies in patients with solid tumours who are included …

Primary cutaneous lymphoma: recommendations for clinical trial design and staging update from the ISCL, USCLC, and EORTC

EA Olsen, S Whittaker, R Willemze… - Blood, The Journal …, 2022 - ashpublications.org
The number of patients with primary cutaneous lymphoma (PCL) relative to other non-
Hodgkin lymphomas (NHLs) is small and the number of subtypes large. Although clinical …

Excellent outcome of young children with nodular desmoplastic medulloblastoma treated on “Head Start” III: a multi-institutional, prospective clinical trial

G Dhall, SH O'Neil, L Ji, K Haley, AM Whitaker… - Neuro …, 2020 - academic.oup.com
Abstract Background “Head Start” III, was a prospective clinical trial using intensive induction
followed by myeloablative chemotherapy and autologous hematopoietic cell rescue …

[HTML][HTML] Unlocking the power of artificial intelligence and big data in medicine

C Lovis - Journal of medical Internet research, 2019 - jmir.org
Data-driven science and its corollaries in machine learning and the wider field of artificial
intelligence have the potential to drive important changes in medicine. However, medicine is …

An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancer

BE Johnson, AL Creason, JM Stommel, JM Keck… - Cell Reports …, 2022 - cell.com
Mechanisms of therapeutic resistance and vulnerability evolve in metastatic cancers as
tumor cells and extrinsic microenvironmental influences change during treatment. To …

Discrepant assessments of progressive disease in clinical trials between routine clinical reads and formal RECIST 1.1 interpretations

MJ Siegel, JE Ippolito, RL Wahl… - Radiology: Imaging …, 2023 - pubs.rsna.org
Purpose To analyze the frequency of discrepant interpretations of progressive disease (PD)
between routine clinical and formal Response Evaluation Criteria in Solid Tumors (RECIST) …

Performance of an automated registration-based method for longitudinal lesion matching and comparison to inter-reader variability

DT Huff, V Santoro-Fernandes, S Chen… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective. Patients with metastatic disease are followed throughout treatment with medical
imaging, and accurately assessing changes of individual lesions is critical to properly inform …

Challenges, complexities, and considerations in the design and interpretation of late-phase oncology trials

TA Lin, AD Sherry, EB Ludmir - Seminars in radiation oncology, 2023 - Elsevier
Optimal management of cancer patients relies heavily on late-phase oncology randomized
controlled trials. A comprehensive understanding of the key considerations in designing and …

Monitoring of circulating tumour DNA in advanced pancreatic ductal adenocarcinoma predicts clinical outcome and reveals disease progression earlier than …

KH Edland, K Tjensvoll, S Oltedal, I Dalen… - Molecular …, 2023 - Wiley Online Library
Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with a need for better tools to
guide treatment selection and follow‐up. The aim of this prospective study was to investigate …