A review of the common neurodegenerative disorders: current therapeutic approaches and the potential role of nanotherapeutics

RNL Lamptey, B Chaulagain, R Trivedi… - International journal of …, 2022 - mdpi.com
Neurodegenerative disorders are primarily characterized by neuron loss. The most common
neurodegenerative disorders include Alzheimer's and Parkinson's disease. Although there …

Alzheimer's disease and its treatment by different approaches: A review

S Srivastava, R Ahmad, SK Khare - European Journal of Medicinal …, 2021 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder that impairs mental ability
development and interrupts neurocognitive function. This neuropathological condition is …

Recent applications of PLGA based nanostructures in drug delivery

M Mir, N Ahmed, A ur Rehman - Colloids and Surfaces B: Biointerfaces, 2017 - Elsevier
Over the years, issues associated with non-biodegradable polymers have paved the way for
biodegradable polymers in the domain of pharmaceutical and biomedical sciences. Poly …

Advancements in nanotherapeutics for Alzheimer's disease: current perspectives

S Harilal, J Jose, DGT Parambi, R Kumar… - Journal of Pharmacy …, 2019 - academic.oup.com
Objectives Considerable progress has been made in the treatment of Alzheimer's disease
(AD), but all available strategies focus on alleviating symptoms rather than curing, which …

Chitin and chitosan derivatives as biomaterial resources for biological and biomedical applications

S Satitsri, C Muanprasat - Molecules, 2020 - mdpi.com
Chitin is a long-chain polymer of N-acetyl-glucosamine, which is regularly found in the
exoskeleton of arthropods including insects, shellfish and the cell wall of fungi. It has been …

Concepts and practices used to develop functional PLGA-based nanoparticulate systems

H Sah, LA Thoma, HR Desu, E Sah… - International journal of …, 2013 - Taylor & Francis
The functionality of bare polylactide-co-glycolide (PLGA) nanoparticles is limited to drug
depot or drug solubilization in their hard cores. They have inherent weaknesses as a drug …

Current advances in the development of novel polymeric nanoparticles for the treatment of neurodegenerative diseases

A Cano, E Sanchez-Lopez, M Ettcheto… - …, 2020 - Taylor & Francis
Effective intervention is essential to combat the coming epidemic of neurodegenerative (ND)
diseases. Nanomedicine can overcome restrictions of CNS delivery imposed by the blood …

Therapeutic potential of phytoconstituents in management of Alzheimer's disease

AK Singh, SN Rai, A Maurya, G Mishra… - Evidence‐Based …, 2021 - Wiley Online Library
Since primitive times, herbs have been extensively used in conventional remedies for
boosting cognitive impairment and age‐associated memory loss. It is mentioned that …

Nanomaterials for reducing amyloid cytotoxicity

M Zhang, X Mao, Y Yu, CX Wang, YL Yang… - Advanced …, 2013 - Wiley Online Library
This review is intended to reflect the recent progress on therapeutic applications of
nanomaterials in amyloid diseases. The progress on anti‐amyloid functions of various …

Exosome-based approaches in the management of Alzheimer's disease

R Kandimalla, M Saeed, N Tyagi, RC Gupta… - … & Biobehavioral Reviews, 2023 - Elsevier
Alzheimer's disease (AD) has been the most extensively studied neurological disorders that
affects millions of individuals globally and is associated with misfolding of proteins in the …