Dendritic-cells (DCs) have received considerable attention as potential targets for the
development of anticancer vaccines. DC-based anticancer vaccination relies on patient …

APPROXIMATELY 10,000 autologous hematopoietic stem cell (HSC) transplants are
performed worldwide each year for malignant diseases. 1 Results of randomized trials in …

Dendritic cell (DC)-based vaccination for cancer treatment has seen considerable
development over recent decades. However, this field is currently in a state of flux toward …

In recent years, great strides in understanding and regulating the immune system have led
to new hope for harnessing its exquisite specificity to destroy cancer cells without affecting …

Dendritic cell (DC)-based vaccines against cancer have been extensively developed over
the past two decades. Typically DC-based cancer immunotherapy entails loading patient …

Dendritic cells (DCs) occupy a central position in the immune system, orchestrating a wide
repertoire of responses that span from the development of self-tolerance to the elicitation of …

Polarization of an immune response toward tolerance or immunity is dictated by the
interactions between T cells and dendritic cells (DC), which in turn are modulated by the …

The use of tumor antigen loaded dendritic cells (DC) is one of the most promising
approaches to induce a tumor specific immune response in vivo. Several strategies have …

Importance of the field: Novel approaches are needed for patients with small cell lung
cancer (SCLC), as response after relapse is poor with standard therapies. p53 gene …

Recombinant adenoviral vectors have promise for human gene therapy because of efficient
transgene expression in nondividing primary cell types. Dendritic cells (DC) have potential …