Ependymal tumors are rare CNS tumors and may occur at any age, but their proportion
among primary brain tumors is highest in children and young adults. Thus, the level of …

Relative biological effectiveness in proton beam therapy – Current knowledge and future
challenges - Clinical and Translational Radiation Oncology Skip to Main Content Skip to Main …

Purpose Dosimetric studies show that proton therapy can reduce the low/intermediate
radiation dose to uninvolved tissue in children with low-grade glioma (LGG). For this reason …

Purpose To investigate if radiographic imaging changes defined as necrosis correlate with
regions in the brain with elevated linear energy transfer (LET) for proton radiation therapy …

Proton beam therapy is a highly conformal form of radiation therapy, which currently
represents an important therapeutic component in multidisciplinary management in …

Abstract Aims In 2008, the UK National Health Service started the Proton Overseas
Programme (POP), to provide access for proton beam therapy (PBT) abroad for selected …

Aims Childhood cancer is rare and survival of childhood cancer has increased up to 80% at
5 years after diagnosis. Radiotherapy is an important element of the multimodal treatment …

Objectives: High-energy Proton Beam Therapy (PBT) commenced in England in 2018 and
NHS England commissions PBT for 1.5% of patients receiving radical radiotherapy. We …

Purpose: In radiotherapy (RT) for brain tumors, patient heterogeneity masks treatment
effects, complicating the prediction and mitigation of radiation-induced brain necrosis …

The UK has an important role in the evaluation of proton beam therapy (PBT) and takes its
place on the world stage with the opening of the first National Health Service (NHS) PBT …