Recent advances in the development of pyrazole derivatives as anticancer agents
Y Zhang, C Wu, N Zhang, R Fan, Y Ye, J Xu - International Journal of …, 2023 - mdpi.com
Pyrazole derivatives, as a class of heterocyclic compounds, possess unique chemical
structures that confer them with a broad spectrum of pharmacological activities. They have …
structures that confer them with a broad spectrum of pharmacological activities. They have …
Copper pyrazole complexes as potential anticancer agents: evaluation of cytotoxic response against cancer cells and their mechanistic action at the molecular level
M Ghorbanpour, A Shayanfar, B Soltani - Coordination Chemistry Reviews, 2024 - Elsevier
This review-based study presents the anticancer potential of pyrazole-based copper
complexes, aiming to evaluate their mechanistic action at the molecular level and find …
complexes, aiming to evaluate their mechanistic action at the molecular level and find …
Dinuclear doubly bridged phenoxido copper (II) complexes as efficient anticancer agents
SS Massoud, FR Louka, NMH Salem… - European Journal of …, 2023 - Elsevier
Abstract Two cationic [Cu 2 (L 1-2) 2](ClO 4) 2 (1, 2), and four neutral doubly bridged-
phenoxido-copper (II) complexes [Cu 2 (L 3-4) 2](3, 4) and [Cu 2 (L 5-6) 2 (H 2 O)]‧ 2H 2 O …
phenoxido-copper (II) complexes [Cu 2 (L 3-4) 2](3, 4) and [Cu 2 (L 5-6) 2 (H 2 O)]‧ 2H 2 O …
Copper-instigated modulatory cell mortality mechanisms and progress in oncological treatment investigations
L Gao, A Zhang - Frontiers in Immunology, 2023 - frontiersin.org
Copper, a transition metal, serves as an essential co-factor in numerous enzymatic active
sites and constitutes a vital trace element in the human body, participating in crucial life …
sites and constitutes a vital trace element in the human body, participating in crucial life …
Metal complexes derived from bidentate ligands: Synthesis, catalytic and biological applications
DI Ugwu, J Conradie - Inorganica Chimica Acta, 2023 - Elsevier
This review focusses on metal complexes containing bidentate ligands. The development in
the synthesis and some applications of these complexes, reported mainly in the last two …
the synthesis and some applications of these complexes, reported mainly in the last two …
Coordination behavior of cocaine toward d-block metal ions: synthesis, spectral analysis, density functional theory (DFT) studies, and chemotherapeutic activity
The exploration of novel bioactive metallopharmaceuticals for the treatment of diseases
such as microbial infections or cancer, with a focus on reducing side effects and drug …
such as microbial infections or cancer, with a focus on reducing side effects and drug …
An updated overview on nitrogen-rich azole-based gold coordination complexes as potent anticancer agents
M Ghorbanpour, B Soltani - Coordination Chemistry Reviews, 2025 - Elsevier
The ability of gold-based complexes in diagnosis and treatment of cancers as the main
worldwide health problems, along with the successful clinical reports of bioactive azole …
worldwide health problems, along with the successful clinical reports of bioactive azole …
Copper (ii) complexes of the CuN 4 S core: selective cytotoxicity to cancerous cells, ROS generation and induction of apoptosis
Eight novel mixed-ligand copper (II) complexes of the type [Cu (L)(phen)](ClO4)(1–8)
synthesized from S-methyldithiocarbazate Schiff bases [H (L1)–H (L8)] and 1, 10 …
synthesized from S-methyldithiocarbazate Schiff bases [H (L1)–H (L8)] and 1, 10 …
Synthesis, Crystal Structure and Antibacterial Activity of Cu (II) Complex with Nitrogen Donor Pyrazolyl Borate Derivatives
B Soltani, M Ghorbanpour, S Bagheri… - Pharmaceutical …, 2023 - publish.journalgazett.co.in
Background: Pyrazolyl borate derivatives are versatile ligands that can be coordinated with
transition metals and formated a variety of different coordination modes. Copper complexes …
transition metals and formated a variety of different coordination modes. Copper complexes …
Coordination Behavior of Cocaine Toward d-Block Metal Ions: Synthesis, Spectral Analysis, DFT Studies, And Chemotherapeutic Activity
The study of new bioactive metallopharmaceuticals for the treatment of diseases like
microbial infections or cancer with a reduction in side effects and drug resistance is an active …
microbial infections or cancer with a reduction in side effects and drug resistance is an active …