The immune system is generally known to be the primary defense mechanism against
pathogens. Any pathological conditions are reflected in anomalies in the immune system …

Purpose There is a growing amount of evidence to suggest that inflammation may have a
role in the onset and prognosis of psychiatric disorders. We reviewed the literature of studies …

We performed a systematic analysis of blood DNA methylation profiles from 4483
participants from seven independent cohorts identifying differentially methylated positions …

Background In psychotic and mood disorders, immune alterations are hypothesized to
underlie cognitive symptoms, as they have been associated with elevated blood levels of …

Innate immunity has been linked to initiation of Alzheimer's disease and multiple sclerosis.
Moreover, risk of first-episode psychosis (FEP) and schizophrenia (Sz) is increased after …

Background The possible associations between depression and neutrophil to lymphocyte
ratio (NLR), platelet to lymphocyte ratio (PLR), and monocyte to lymphocyte ratio (MLR) …

Neutrophil–lymphocyte ratio (NLR), platelet–lymphocyte ratio (PLR), monocyte–lymphocyte
ratio (MLR) and systemic immune-inflammation index (SII index) are increasingly used as …

Background Insulin resistance predisposes to cardiometabolic disorders, which are
commonly comorbid with schizophrenia and are key contributors to the significant excess …

Objectives The main objective of this study was to compare neutrophil–lymphocyte ratio
(NLR), a marker of systemic inflammation, between patients diagnosed with International …

Schizophrenia is a debilitating psychiatric illness that remains poorly understood. While the
bulk of symptomatology has classically been associated with disrupted brain functioning …