The complex pathobiology underlying cardiovascular diseases (CVDs) has yet to be
explained. Aberrant epigenetic changes may result from alterations in enzymatic activities …

Nearly all cardiovascular diseases show sexual dimorphisms in prevalence, presentation,
and outcomes. Until recently, most clinical trials were carried out in males, and many animal …

Cardiogenesis is a tightly regulated dynamic process through a continuum of differentiation
and proliferation events. Key factors and pathways governing this process remain …

How transcription factors attain their target gene specificity and how this specificity may be
modulated, acquiring different regulatory functions through the development of plant tissues …

Chromatin remodeling and genomic alterations impact spatio-temporal regulation of gene
expression, which is central to embryonic development. The analysis of mouse and chicken …

Cardiomyopathies are a group of common heart disorders that affect numerous people
worldwide. Left ventricular non-compaction (LVNC) is a structural disorder of the ventricular …

Transcriptomic approaches can give insight into molecular mechanisms underlying
chemical toxicity and are increasingly being used as part of toxicological assessments. To …

Cardiac hypoxia plays a significant role in various types of heart disease, and improper
treatment of hypoxia often leads to myocardial cell damage or even death. Transcriptome …

Opium poppy (Papaver somniferum) is a flowering plant in the Papaveraceae family that has
been valued for its ornamental and significant medicinal properties for thousands of years …

Background During development a pool of precursors form a heart with atrial and ventricular
chambers that exhibit distinct transcriptional and electrophysiological properties. Normal …