Background Thorough irrigation and debridement using an irrigation solution is a well-
established treatment for both acute and chronic periprosthetic joint infections (PJIs). In the …

Background Periprosthetic joint infection remains a significant challenge for arthroplasty
surgeons globally. Over the last few decades, there has been much advancement in terms of …

Background A diverse array of antibacterial solutions is utilized by orthopedic surgeons in
an attempt to disperse bacterial biofilm. Few studies compare these agents against biofilm …

Aims Current treatments of prosthetic joint infection (PJI) are minimally effective against
Staphylococcus aureus biofilm. A murine PJI model of debridement, antibiotics, and implant …

Irrigation and debridement in the treatment of periprosthetic joint infection (PJI) serve an
integral role in the eradication of bacterial burden and subsequent re-infection rates …

The increasing incidence of periprosthetic joint infections (PJIs) has led to a growing interest
in developing strategies to prevent and treat this severe complication. The surgical site's …

Background Antiseptic irrigation solutions are commonly used by arthroplasty surgeons to
reduce intraoperative bacterial colonization with the goal of reducing postoperative …

Implementation of strategies for prevention of surgical site infection and periprosthetic joint
infection is gaining further attention. We provide an overview of the pertinent evidence …

Staphyloccocus aureus is one of the major pathogens in orthopedic periprosthetic joint
infection (PJI), a devastating complication of total joint arthroplasty that often results in …

There is controversial clinical evidence regarding the added antibacterial benefit of locally
administering antiseptic solutions or antibiotics to the infected joint space. The objectives of …