[HTML][HTML] Cell fate decisions, transcription factors and signaling during early retinal development
R Diacou, P Nandigrami, A Fiser, W Liu… - Progress in retinal and …, 2022 - Elsevier
The development of the vertebrate eyes is a complex process starting from anterior-posterior
and dorso-ventral patterning of the anterior neural tube, resulting in the formation of the eye …
and dorso-ventral patterning of the anterior neural tube, resulting in the formation of the eye …
Specialized subpopulations of deep-layer pyramidal neurons in the neocortex: bridging cellular properties to functional consequences
Neocortical pyramidal neurons with somata in layers 5 and 6 are among the most visually
striking and enigmatic neurons in the brain. These deep-layer pyramidal neurons (DLPNs) …
striking and enigmatic neurons in the brain. These deep-layer pyramidal neurons (DLPNs) …
A multimodal cell census and atlas of the mammalian primary motor cortex
Principal manuscript editors, Analysis coordination… - Nature, 2021 - nature.com
Here we report the generation of a multimodal cell census and atlas of the mammalian
primary motor cortex as the initial product of the BRAIN Initiative Cell Census Network …
primary motor cortex as the initial product of the BRAIN Initiative Cell Census Network …
Genetic dissection of the glutamatergic neuron system in cerebral cortex
Diverse types of glutamatergic pyramidal neurons mediate the myriad processing streams
and output channels of the cerebral cortex,, yet all derive from neural progenitors of the …
and output channels of the cerebral cortex,, yet all derive from neural progenitors of the …
Chromosome 10q26–driven age-related macular degeneration is associated with reduced levels of HTRA1 in human retinal pigment epithelium
BL Williams, NA Seager, JD Gardiner… - Proceedings of the …, 2021 - National Acad Sciences
Genome-wide association studies have identified the chromosome 10q26 (Chr10) locus,
which contains the age-related maculopathy susceptibility 2 (ARMS2) and high temperature …
which contains the age-related maculopathy susceptibility 2 (ARMS2) and high temperature …
Extensive transcriptional and chromatin changes underlie astrocyte maturation in vivo and in culture
M Lattke, R Goldstone, JK Ellis, S Boeing… - Nature …, 2021 - nature.com
Astrocytes have essential functions in brain homeostasis that are established late in
differentiation, but the mechanisms underlying the functional maturation of astrocytes are not …
differentiation, but the mechanisms underlying the functional maturation of astrocytes are not …
[HTML][HTML] Regulatory roles for SOX11 in development, stem cells and cancer
SM Tsang, E Oliemuller, BA Howard - Seminars in cancer biology, 2020 - Elsevier
The transcription factor SOX11 (SRY-related high-mobility-group (HMG) box 11), a member
of the SOXC group, is expressed during embryogenesis but largely absent in most adult …
of the SOXC group, is expressed during embryogenesis but largely absent in most adult …
Chromatin remodeling complex NuRD in neurodevelopment and neurodevelopmental disorders
A Hoffmann, D Spengler - Frontiers in genetics, 2019 - frontiersin.org
The nucleosome remodeling and deacetylase (NuRD) complex presents one of the major
chromatin remodeling complexes in mammalian cells. Here, we discuss current evidence for …
chromatin remodeling complexes in mammalian cells. Here, we discuss current evidence for …
A comprehensive temporal patterning gene network in Drosophila medulla neuroblasts revealed by single-cell RNA sequencing
During development, neural progenitors are temporally patterned to sequentially generate a
variety of neural types. In Drosophila neural progenitors called neuroblasts, temporal …
variety of neural types. In Drosophila neural progenitors called neuroblasts, temporal …
RbAp48 protein is a critical component of GPR158/OCN signaling and ameliorates age-related memory loss
S Kosmidis, A Polyzos, L Harvey, M Youssef… - Cell reports, 2018 - cell.com
Precisely deciphering the molecular mechanisms of age-related memory loss is crucial to
create appropriate therapeutic interventions. We have previously shown that the histone …
create appropriate therapeutic interventions. We have previously shown that the histone …