Microfluidic systems for blood and blood cell characterization

H Kim, A Zhbanov, S Yang - Biosensors, 2022 - mdpi.com
A laboratory blood test is vital for assessing a patient's health and disease status. Advances
in microfluidic technology have opened the door for on-chip blood analysis. Currently …

Towards quantitative small-animal imaging on hybrid PET/CT and PET/MRI systems

M Amirrashedi, H Zaidi, MR Ay - Clinical and Translational Imaging, 2020 - Springer
Aim Over the past two decades, innovations in small-animal positron emission tomography
(PET) have reached an impressive level, which has brought countless opportunities to …

Investigation of air bubble behaviour after gas embolism events induced in a microfluidic network mimicking microvasculature

MM Mardanpour, AS Perumal, Z Mahmoodi, K Baassiri… - Lab on a Chip, 2024 - pubs.rsc.org
Gas embolism is a medical condition that occurs when gas bubbles are present in veins or
arteries, decreasing blood flow and potentially reducing oxygen delivery to vital organs …

Experimental study of liquid–liquid dispersion patterns in T-inlet microchannels with different junction angles

W Cao, Q Yang, D Yang, X Wang, Q Mao - Experimental Thermal and Fluid …, 2024 - Elsevier
Liquid-liquid two-phase flow in T-inlet microchannels with different junction angles (θ= 30°,
60°, 90°, 120° and 150°) was investigated experimentally. Four flow regimes of the …

Flow radiocytometry using droplet optofluidics

B Ha, TJ Kim, E Moon, AJ Giaccia, G Pratx - Biosensors and Bioelectronics, 2021 - Elsevier
Flow-based cytometry methods are widely used to analyze heterogeneous cell populations.
However, their use for small molecule studies remains limited due to bulky fluorescent labels …

A mini-panel PET scanner-based microfluidic radiobioassay system allowing high-throughput imaging of real-time cellular pharmacokinetics

Z Liu, P Zhang, H Ji, Y Long, B Jing, L Wan, D Xi, R An… - Lab on a Chip, 2020 - pubs.rsc.org
On-chip radiometric detection of biological samples using radiotracers has become an
emerging research field known as microfluidic radiobioassays. Performing parallel …

Microfluidics-Coupled Radioluminescence Microscopy for In Vitro Radiotracer Kinetic Studies

TJ Kim, B Ha, AD Bick, M Kim, SKY Tang… - Analytical …, 2021 - ACS Publications
Integrated bioassay systems that combine microfluidics and radiation detectors can deliver
medical radiopharmaceuticals to live cells with precise timing, while minimizing radiation …

Simulation of Droplet Formation in T‐Inlet Microchannels with Different Junction Angle

Q Yang, W Cao, Q Mao - Chemical Engineering & Technology, 2022 - Wiley Online Library
The level set method was used to numerically simulate the droplet formation process in T‐
junction microchannels with different junction angle. The effects of flow rate ratio, capillary …

Development of a lensless radiomicroscope for cellular-resolution radionuclide imaging

JS Klein, TJ Kim, G Pratx - Journal of Nuclear Medicine, 2023 - Soc Nuclear Med
The action of radiopharmaceuticals takes place at the level of cells. However, existing
radionuclide assays can only measure uptake in bulk or in small populations of single cells …

The ultra high sensitivity blood counter: a compact, MRI-compatible, radioactivity counter for pharmacokinetic studies in μl volumes

L Convert, O Sarrhini, M Paillé, N Salem… - Biomedical Physics …, 2022 - iopscience.iop.org
Quantification of physiological parameters in preclinical pharmacokinetic studies based on
nuclear imaging requires the monitoring of arterial radioactivity over time, known as the …