Mechanistic insights into the inhibition of quercetin on xanthine oxidase

C Zhang, R Wang, G Zhang, D Gong - International journal of biological …, 2018 - Elsevier
Quercetin, one of the most abundant flavonoid in the daily diet, was found to reversibly
inhibit the generation of uric acid and superoxide radicals (O 2−) catalyzed by xanthine …

Cascade nanozymatic network mimicking cells with selective and linear perception of H 2 O 2

C Zhu, Z Zhou, XJ Gao, Y Tao, X Cao, Y Xu, Y Shen… - Chemical …, 2023 - pubs.rsc.org
A single stimulus leading to multiple responses is an essential function of many biological
networks, which enable complex life activities. However, it is challenging to duplicate a …

Palladium/rhodium/iridium trimetallic octahedral nanozymes exhibiting enhanced peroxidase-like activity for detecting total antioxidant capacity in food

L Yang, ZH Yang, J He, Q Cao, R Zhang… - ACS Applied Nano …, 2023 - ACS Publications
Nanozymes are widely used in detecting biomarkers. However, designing nanozymes
exhibiting high peroxidase-like activity is challenging. This study aimed to synthesize two …

Synthesis of amorphous/crystalline hetero‐phase nanozymes with peroxidase‐like activity by coordination‐driven self‐assembly for biosensors

W Yang, L Zhu, M Yang, W Xu - Small, 2023 - Wiley Online Library
Nanozymes and amorphous nanomaterials attract great attention owing to their
extraordinary properties. However, the requirements for special synthesis conditions …

Inhibition mechanism of baicalein and baicalin on xanthine oxidase and their synergistic effect with allopurinol

N Zeng, G Zhang, X Hu, J Pan, Z Zhou… - Journal of Functional …, 2018 - Elsevier
Suppression of xanthine oxidase (XO) may contribute to control hyperuricemia and gout. In
this study, baicalein and baicalin, two dietary flavones, were found to inhibit the formation of …

Self‐assembling catalytic peptide nanomaterials capable of highly efficient peroxidase activity

O Zozulia, LR Marshall, I Kim, EM Kohn… - … A European Journal, 2021 - Wiley Online Library
The self‐assembly of short peptides gives rise to versatile nanomaterials capable of
promoting efficient catalysis. We have shown that short, seven‐residue peptides bind hemin …

[HTML][HTML] Spatially confined enzymatic tandem system with GOx and HRP compartmentalized in ultrafiltration membrane

S Barricella, JM Fuertes, KH Putera, AE Quigley… - Journal of Membrane …, 2024 - Elsevier
The precise control of timely and spatially defined enzymatic reactions is of considerable
interest in biology, biomedical engineering, and bio-catalysis. In this study, we report a …

[HTML][HTML] Dye-decolorizing peroxidase of Thermobifida halotolerance displays complex kinetics with both substrate inhibition and apparent positive cooperativity

H Pupart, T Lukk, P Väljamäe - Archives of Biochemistry and Biophysics, 2024 - Elsevier
Dye-decolorizing peroxidases (DyPs) have been intensively investigated for the purpose of
industrial dye decolourization and lignin degradation. Unfortunately, the characterization of …

Mechanism of fisetin suppressing superoxide anion and xanthine oxidase activity

N Zeng, G Zhang, X Hu, J Pan, D Gong - Journal of Functional Foods, 2019 - Elsevier
Excessive activity of xanthine oxidase (XO) will promote the formation of uric acid and
superoxide anion (O 2−), which may cause hyperuricemia and oxidative damage. Fisetin, a …

Peroxidase-and UV-triggered oxidase mimetic activities of the UiO-66-NH 2/chitosan composite membrane for antibacterial properties

X Wang, X Zhou, K Yang, Q Li, R Wan, G Hu… - Biomaterials …, 2021 - pubs.rsc.org
In this study, UiO-66-NH2 metal–organic framework (MOF) nanoparticles with peroxidase
and oxidase mimetic activities were incorporated into a chitosan (CS) matrix by a simple and …