From early life to adulthood, the microbiota play a crucial role in the health of the infant. The
microbiota in early life are not only a key regulator of infant health but also associated with …

The innate immune system is the oldest protection strategy that is conserved across all
organisms. Although having an unspecific action, it is the first and fastest defense …

The microbiomes of cesarean-born infants differ from vaginally delivered infants and are
associated with increased disease risks. Vaginal microbiota transfer (VMT) to newborns may …

The microbiome has been proven to be associated with many diseases and has been used
as a biomarker and target in disease prevention and intervention. Currently, the vital role of …

There is growing appreciation of key roles of the gut microbiota in maintaining homeostasis
and influencing brain and behaviour at critical windows across the lifespan. Mounting …

Background Birth by caesarean section (CS) is associated with aberrant gut microbiome
development and greater disease susceptibility later in life. We investigated whether oral …

Antimicrobial resistance (AMR) is an accelerating global threat, yet the nature of AMR in the
gut microbiome and how AMR is acquired during early life remain largely unknown. In a …

Acute lymphoblastic leukaemia (ALL) is the most common cancer of childhood. Here, we
map emerging evidence suggesting that children with ALL at the time of diagnosis may have …

Humans are colonised by a highly adapted microbiota with coevolved functions that promote
human health, development and disease resistance. Acquisition and assembly of the …

Environmental exposures during pregnancy that alter both the maternal gut microbiome and
the infant's risk of allergic disease and asthma include a traditional farm environment and …