Disease-modifying anti-asthmatic drugs

M Lommatzsch, GG Brusselle, GW Canonica… - The Lancet, 2022 - thelancet.com
Drugs available for asthma treatment in the first decades of the 20th century
(sympathomimetic agents such as oral ephedrine, intravenous adrenaline, or inhaled …

JAK inhibitors for asthma

SN Georas, P Donohue, M Connolly… - Journal of allergy and …, 2021 - Elsevier
Asthma is an inflammatory disease of the airways characterized by intermittent episodes of
wheezing, chest tightness, and cough. Many of the inflammatory pathways implicated in …

Impact of comorbid asthma on severity of coronavirus disease (COVID-19)

SC Lee, KJ Son, CH Han, JY Jung, SC Park - Scientific reports, 2020 - nature.com
The severity of the coronavirus disease (COVID-19) is associated with various comorbidities.
However, no studies have yet demonstrated the potential risk of respiratory failure and …

Expert consensus on the tapering of oral corticosteroids for the treatment of asthma. A Delphi study

CM Suehs, A Menzies-Gow, D Price… - American journal of …, 2021 - atsjournals.org
Rationale: There is a need to minimize oral corticosteroid (OCS) use in patients with asthma
to prevent their costly and burdensome adverse effects. Current guidelines do not provide …

Executive summary: Japanese guidelines for adult asthma (JGL) 2021

A Niimi, K Fukunaga, M Taniguchi… - Allergology …, 2023 - jstage.jst.go.jp
abstract Asthma is characterized by chronic airway inflammation, variable airway narrowing,
and sensory nerve irritation, which manifest as wheezing, dyspnea, chest tightness, and …

Short-course systemic corticosteroids in asthma: striking the balance between efficacy and safety

D Price, M Castro, A Bourdin, S Fucile… - European Respiratory …, 2020 - Eur Respiratory Soc
Short courses of systemic corticosteroids (SCS), both oral and injectable, are very effective
for the resolution of acute asthma symptoms, including exacerbations. However, the benefits …

[HTML][HTML] Systemic corticosteroids in asthma: a call to action from World Allergy Organization and Respiratory Effectiveness Group

ER Bleecker, M Al-Ahmad, L Bjermer… - World Allergy …, 2022 - Elsevier
Systemic corticosteroids (SCS) are a highly effective treatment for acute exacerbations and
long-term symptom control in asthma. Long-term SCS use is highly prevalent across all …

Bringing asthma care into the twenty-first century

K Larsson, H Kankaanranta, C Janson… - NPJ primary care …, 2020 - nature.com
Despite access to diagnostic tests and effective therapies, asthma often remains
misdiagnosed and/or poorly controlled or uncontrolled. In this review, we address the key …

Observational UK cohort study to describe intermittent oral corticosteroid prescribing patterns and their association with adverse outcomes in asthma

H Heatley, TN Tran, A Bourdin, A Menzies-Gow… - Thorax, 2023 - thorax.bmj.com
Introduction Oral corticosteroids (OCS) for asthma are associated with increased risks of
developing adverse outcomes (adverse outcomes); no previous study has focused …

Definitions of non-response and response to biological therapy for severe asthma: a systematic review

E Khaleva, A Rattu, C Brightling, A Bush… - ERJ open …, 2023 - Eur Respiratory Soc
Background Biologics have proven efficacy for patients with severe asthma but there is lack
of consensus on defining response. We systematically reviewed and appraised …